مرکز تحقیقات نانو فناوری

امتیاز کاربران

ستاره غیر فعالستاره غیر فعالستاره غیر فعالستاره غیر فعالستاره غیر فعال

 

 

رئیس مرکز تحقیقات نانوفناوری

دکتر محمود رضا جعفری

 استاد گروه فارماسیوتیکس دانشکده داروسازی

این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید
 

 

دکتر محمد رمضانی

 استاد گروه بیوتکتولوژی دارویی

این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید

   

دکتر بیژن ملائکه

 استاد گروه فارماسیوتیکس

این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید

    

دکتر علی بدیعی

 دانشیار گروه فارماسیوتیکس

این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید

    

دکتر محسن تفقدی

 استاد گروه فارماسیوتیکس

این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید

    

دکتر شیوا گل محمد زاده

 استاد  گروه فارماسیوتیکس

این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید

                  

دکتر مریم هاشمی

 استادیار گروه بیوتکنولوژی دارویی

این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید
 

دکتر زهرا سلماسی

 استادیارگروه نانوتکنولوژی دارویی

این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید
 

دکتر سیده هدی علوی زاده

 استادیار گروه نانوتکنولوژی دارویی

این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید
 

دکتر لیلا عربی

 استادیار گروه نانوتکنولوژی دارویی

این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید
 

دکتر فاطمه غیبی

 استادیار گروه نانو پزشکی

این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید

 

دکتر سیده عالیا موسویان

استادیار گروه فارماسیوتیکس

این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید

                 

 

 اعظم عباسی

کارشناس آزمایشگاه

این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید

 

زهرا صابری

کارشناس آزمایشگاه و کارشناس پژوهشی

این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید

 

امتیاز کاربران

ستاره غیر فعالستاره غیر فعالستاره غیر فعالستاره غیر فعالستاره غیر فعال

CURRICULUM VITAE

 

PERSONAL DETAILS

 

Name:

Mohammad Ramezani

 

Nationality:

 

Iranian

 

Correspondence Address:

 

Pharmaceutical Research Center, School of Pharmacy, P.O Box: 91775-1365

Mashhad, Iran

 

 

EDUCATION AND QUALIFICATIONS

 

1983-1988

School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

 

1988

 

Pharm.D. awarded.

 

1992-1996

 

Department of Chemistry, Dalhousie Universitry, Halifax, NS, Canada

 

1996

 

Ph.D. awarded.

 

2003-2004

 

Postdoctoral associate, Gene delivery, University of Minnesota, Minneapolis, MN, USA

 

RESEARCH EXPERIENCES

 

 

1996 up to now

 

Supervision of 20 Ph.D. and 65 Pharm.D. students working on their theses.

 

 

Currently I am involved in:

a) Design, synthesis and testing of

    Non-viral vectors for gene delivery

b) Proteomics analysis

 

 

 

PROFESSIONAL EXPERIENCES

 

1988-1992

 

 

1996-2000

 

 

2001-2005

 

 

2006 up to now

 

 

Instructor of Pharmacognosy, School of Pharmacy, Mashhad, Iran.

 

Assistant Professor in Pharmaceutical Biotechnology.

 

Associate Professor in Pharmaceutical Biotechnology.

 

Professor in Pharmaceutical Biotechnology

 

PRESENT POSITIONS

 

 

2006 up to now

 

Professor in Pharmaceutical Biotechnology,

1997 to 2003, 2014 to now

Head, Department of Biotechnology, School of Pharmacy, Mashhad, Iran

 

2000 up to now

 

 

 

 

2012 to now

 

2000-2002 , and 2004 to now

 

 

 

1997 to 2014

 

 

 

 

1999 up to now

Director of Nanomedicine Lab, Nanotechnology Research Center, Bu-Ali Research Center, Mashhad University of Medical Science, Mashhad, Iran.

 

Editor-in-Chief, Nanomedicine Journal

 

Head, Pharmaceutical Research Center, Bu-Ali Research Institute

 

 

A member of the Research Council of the Mashhad University of Medical Sciences.

 

 

Editorial Board of Iranian Journal of Basic Medical Sciences.

 

 

2010 to now

 

 

2011 to now

 

 

2010 to now

 

Director, National Board of Pharmaceutical

Biotechnology

 

A member of Iran National Academy of Sciences, Nanotechnology subcommittee

 

A member of Nanotechnology Research Center, Mashhad University of Medical Sciences

 

 

 

RESEARCH INTERESTS

a)    Nanomedicine (Design and synthesis of gene delivery vectors based on polycations, carbon nanotubes and hybride peptides

b)   Aptamer-based biosensors

c)    Proteomics analysis

 

Awards

 

 

 

 

 

National:

a)    Best Investigator Prize, The 15th Razi Research Festival on Medical Sciences

 

University:

a)    Best Investigator Prize in 2006, 2010, 2011, 2012, 2013 among all faculty member of Mashhad University of Medical Sciences.

b)    Best published article in 2010.

c)    3rd highest H-Index in 2011, 2012 and 2013.

 

 

 

REFERENCES

1. Professor W. Thomas Shier, Department of Medicinal Chemistry, College of Pharmacy,

University of Minnesota, Minneapolis, MN 55455, USA, e-mail: این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید

 

2. Professor Ernst Wagner, Chair, Pharmaceutical Biotechnology
Munich Center for System-based Drug Research, Center for Nanoscience, Ludwig-Maximilians-Universität, Butenandtstr. 5-13, Building D, Room 3.030
D-81377 Munich, Germany
Tel: +49 89 2180-77841
Fax: +49 89 2180-77798
e-mail: این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید

 

PUBLICATION

 

a) In International Journals:

 

S. M. Taghdisia, N. M. Danesh, P. Lavaee, M. Ramezani, K. Abnous (2016). An electrochemical aptasensor based on gold nanoparticles, thionine and hairpin structure of complementary strand of aptamer for ultrasensitive detection of lead. Sensors and Actuators B: Chemical, 234, 462–469 (IF: 4.76).

 

A. Mokhtarzadeh, M. Tabarzad, J. Ranjbari, M. Guardia, M. Hejazi, M. Ramezani* (2016). Aptamers as smart ligands for nano-carriers targeting. Trends in Analytical Chemistry, 82, 316-327 (IF: 7.478).

 

M. Hasanzadeh, N. Shadjou, A. Mokhtarzadeh, M. Ramezani (2016). Two dimension (2-D) graphene-based nanomaterials as signal amplification elements in electrochemical microfluidic immune-devices: Recent advances. Materials Science and Engineering C, 68, 482-493 (IF: 3.42).

R. Yazdian Robati, A. Arab, M. Ramezani, F. Alebooye Langroodi, K. Abnous, S. M. Taghdisi (2016). Aptasensors for quantitative detection of kanamycin. Biosensors and Bioelectronics, 82, 162–172 (IF: 7.476).

 

S. M. Taghdisi, N. M. Danesh, M. A. Nameghi, M. Ramezani*, K. Abnous (2016), A label-free fluorescent aptasensor for selective and sensitive detection of streptomycin in milk and blood serum. Food Chemistry, 203, 145–149 (IF: 4.052).

 

M. Moghadam, M. Sankian, K. Abnous, A. Varasteh, S. M. Taghdisi, M. Mahmoudi, M. Ramezani, Z. Gholizadeh, A. Ganji  (2016). Cell-SELEX-based selection and characterization of a G-quadruplex DNA aptamer against mouse dendritic cells. International Immunopharmacology, 36, 324–332 (IF: 2.55).

 

S. M. Taghdisi, N. M. Danesh, M. Ramezani, A. S. Emrani, K. Abnous (2016). A novel electrochemical aptasensor based on Y-shape structure of dual-aptamer-complementary strand conjugate for ultrasensitive detection of myoglobin. Biosensors and Bioelectronics, 80, 532–537 (IF: 7.476).

 

M. Bagheri, M. Mohammadi, T.W.J. Steele, M. Ramezani* (2016). Nanomaterial coatings applied on stent surfaces. Nanomedicine, 11(10), 1309–1326 (IF: 4.889).

 

S. M. Taghdisi, N. M. Danesh, M. Ramezani*, P. Lavaee, S. H. Jalalian, R. Yazdian Robati, K. Abnous (2016). Double targeting and aptamer-assisted controlled release delivery of epirubicin to cancer cells by aptamers-based dendrimer in vitro and in vivo. European Journal of Pharmaceutics and Biopharmaceutics, 102, 152–158 (IF: 3.975).

 

S. Askarian, K. Abnous, M. Darroudi, R. K. Oskuee, M. Ramezani* (2016). Gene delivery to neuroblastoma cells by poly (L-lysine)-grafted low molecular weight polyethylenimine copolymers. Biologicals, 44, 212-218 (IF:1.69).

 

V. Soheili, S. M. Taghdisi, M. Hassanzadeh Khayyat, B. S. F. Bazzaz, M. Ramezani*, K. Abnous (2016). Colorimetric and ratiometric aggregation assay for streptomycin using gold nanoparticles and a new and highly specific aptamer. Microchim Acta, 183, 1687–1697 (IF: 4.831).

 

A. Sarreshtehdar Emrani, N. M. Danesh, M. Ramezani, S. M. Taghdisi, K. Abnous (2016). A novel fluorescent aptasensor based on hairpin structure of complementary strand of aptamer and nanoparticles as a signal amplification approach for ultrasensitive detection of cocaine. Biosensors and Bioelectronics, 79(15), 288–293 (IF: 7.476).

 

M. Ramezani, J. Shamsara (2016). Application of DPD in the design of polymeric nano-micelles as drug carriers. Journal of Molecular Graphics and Modeling, 66, 1–8 (IF: 1.674).

 

A. Mokhtarzadeh, A. Alibakhshi, H. Yaghoobi, M. Hashemi, M. Hejazi, M. Ramezani* (2016). Recent advances on biocompatible and biodegradable nanoparticles as gene carriers. Expert Opinion on Biological Therapy, 16(6), 771-785 (IF: 3.438)

 

D. Salarbashi, S. A. Mortazavi, M. Shahidi Noghabi, B. S. Fazly Bazzaz, N. Sedaghat, M. Ramezani, I. Shahabi-Ghahfarrokhi (2016). Development of new active packaging film made from a soluble soybean polysaccharide incorporating ZnO nanoparticles, Carbohydrate Polymers, 140, 220–227 (IF: 4.219).

 

M. Alibolandi, M. Ramezani, K. Abnous, F. Hadizadeh (2016). AS1411 aptamer-decorated biodegradable polyethylene glycol poly (lactic-co-glycolic acid) nanopolymersomes for the targeted delivery of gemcitabine to none small cell lung cancer in vitro. Journal of Pharmaceutical Sciences, 105, 1741-1750 (IF: 3.773).

 

M. Alibolandi, F. Alabdollah, F. Sadeghi, M. Mohammadi, K. Abnous, M. Ramezani*, F. Hadizadeh (2016). Dextran-b-poly (lactide-co-glycolide) polymersome for oral delivery of insulin: In vitro and in vivo evaluation. Journal of Controlled Release, 227, 58-70 (IF: 7.441).

 

A. Hashem Nia, A. Amini, S. Taghavi, H. Eshghi, K. Abnous, M. Ramezani* (2016). A Facile Friedel-Crafts acylation for the synthesis of polyethylenimine-grafted multi-walled carbon nanotubes as efficient gene delivery vectors. International Journal of Pharmaceutics, 502(1–2), 125–137 (IF: 3.994).

S. M. Taghdisi, N. M. Danesh, H. R. Beheshti, M. Ramezani, K. Abnous (2016). A novel fluorescent aptasensor based on gold and silica nanoparticles for the ultrasensitive detection of ochratoxin A. Nanoscale, 8, 3439-3446 (IF: 7.760).

 

M. Ramezani, N. M. Danesh, P. Lavaee, K. Abnous, S. M. Taghdisi (2016). A selective and sensitive fluorescent aptasensor for detection of kanamycin based on catalytic recycling activity of exonuclease III and gold nanoparticles. Sensors and Actuators, B: Chemical, 222, 1-7 (IF: 4.76).

N. M. Danesh, M. Ramezani, A. E. Sarreshtehdar, K. Abnous, S. M. Taghdisi (2016). A novel electrochemical aptasensor based on arch-shape structure of aptamer-complimentary strand conjugate and exonuclease I for sensitive detection of streptomycin. Biosensors and Bioelectronics, 75, 123-128 (IF: 7.476).

M. Teimouri, A. Hashem Nia, K. Abnous, H. Eshghi, M. Ramezani* (2016). Graphene oxide–cationic polymer conjugates: Synthesis and application as gene delivery vectors. Plasmid, 84–85 51–60 (IF: 1.732).

K. Abnous, N. M. Danesh, M. Ramezani, A. E. Sarreshtehdar, S.M. Taghdisi (2016). A novel colorimetric sandwich aptasensor based on an indirect competitive enzyme-free method for ultrasensitive detection of chloramphenicol. Biosensors and Bioelectronics, 78, 80-86 (IF: 7.476).

K. Abnous, N. M. Danesh, M. Ramezani, S. M. Taghdisi, A. S. A. Emrani (2016). A novel electrochemical aptasensor based on H-shape structure of aptamer-complimentary strands conjugate for ultrasensitive detection of cocaine. Sensors and Actuators, B: Chemical, 224, 351-355 (IF: 4.76).

A. S. Emrani, N. M. Danesh, P. Lavaee, M. Ramezani, K. Abnous, S. M. Taghdisi (2016). Colorimetric and fluorescence quenching aptasensors for detection of streptomycin in blood serum and milk based on double-stranded DNA and gold nanoparticles. Food Chemistry, 190, 115-121 (IF: 4.052).

A. Mokhtarzadeh, H. Parhiz, M. Hashemi, K. Abnous, M. Ramezani* (2016). P53-Derived peptides conjugation to PEI: an approach to producing versatile and highly efficient targeted gene delivery carriers into cancer cells. Expert Opinion on Drug Delivery, (in press: doi:10.1517/17425247.2016.1126245) (IF: 5.434)

 

F. Soltani, H. Parhiz, A. Mokhtarzadeh, M. Ramezani* (2015). Synthetic and biological vesicular nano-carriers designed for gene delivery. Current Pharmaceutical Design, 21(42), 6214-6235 (IF: 3.052).

 

M. Khedri, H. Rafatpanah, K. Abnous, P. Ramezani, M. Ramezani* (2015). Cancer immunotherapy via nucleic acid aptamers. International Immunopharmacology, 29 (2), 926–936 (IF: 2.551).

 

S. Askarian, K. Abnous, S. Taghavi, R. K. Oskuee, M. Ramezani* (2015). Cellular delivery of shRNA using aptamer-conjugated PLL-Alkyl–PEI nanoparticles. Colloids and Surfaces B: Biointerfaces. 136, 355-364 (IF: 3.902)

 

S. Ayatollahi, M. Hashemi, R. K. Oskuee, Z. Salmasi, A. Mokhtarzadeh, M. Alibolandi, K. Abnous, M. Ramezani* (2015). Synthesis of efficient gene delivery systems by grafting pegylated

alkylcarboxylate chains to polyamidoamine dendrimers: Evaluation of transfection efficiency and cytotoxicity in cancerous and mesenchymal stem cells. Journal of Biomaterials Applications, 30(5), 632-648 (IF: 1.988).

 

Z. Salmasi, W. T. Shier, M. Hashemi, E. Mahdipour, H. Parhiz, K. Abnous, M. Ramezani* (2015). Heterocyclic amine-modified polyethylenimine as gene carriers for transfection of mammalian cells. European Journal of Pharmaceutics and Biopharmaceutics, 96, 76-88. (IF: 3.975)

 

A. S. EmraniS. M. TaghdisiN. M. DaneshS. H. JalalianM. Ramezani*K. Abnous (2015).  A novel fluorescent aptasensor for selective and sensitive detection of digoxin based on silica nanoparticles. Analytical Methods, 7, 3814-3818 (IF: 1.915)

 

M. Hashemi, S. Ayatollahi, H. Parhiz, A. Mokhtarzade, S. Javidi, M. Ramezani* (2015). PEGylation of Polypropylenimine Dendrimer with Alkylcarboxylate Chain Linkage to Improve DNA Delivery and Cytotoxicity. Applied Biochemistry and Biotechnology, 177 (1), 1-17 (IF: 1.606).

 

M. Alibolandi, K. Abnous, F. Sadeghi, M. Ramezani, F. Hadizadeh (2015). The chemotherapeutic potential of doxorubicin loaded PEG-b-PLGA nanopolymersomes in mouse breast cancer model. European Journal of Pharmaceutics and Biopharmaceutics, 94, 11992, 521-531 (IF: 3.975).

 

M. Khansarizadeh, A. Mokhtarzadeh, M. Rashedinia, S. M. Taghdisi, P. Lari, K. Abnous, M. Ramezani* (2015). Identification of possible cytotoxicity mechanism of polyethylenimine by proteomics analysis. Human and Experimental Toxicology, (published online DOI: 10.1177/0960327115591371)

 

N. M. Danesh, P. Lavaee, M. Ramezani, K. Abnous, S. M. Taghdisi (2015). Targeted and controlled release delivery of daunorubicin to T-cell acute lymphoblastic leukemia by aptamer-modified gold nanoparticles. International Journal of Pharmaceutics, 489, 311-317 (IF: 3.994).

S. M. Taghdisi, N. M. Danesh, P. Lavaee, A. S. Emrani, M. Ramezani*, K. Abnous (2015). A novel colorimetric triple-helix molecular switch aptasensor based on peroxidase-like activity of gold nanoparticles for ultrasensitive detection of lead (II). RSC Advances, 5, 43508-43514 (IF: 3.289).

 

S. M. Taghdisi, N. M. Danesh, A. S. Emrani, M. Ramezani*, K. Abnous (2015). A novel electrochemical aptasensor based on single-walled carbon nanotubes, gold electrode and complimentary strand of aptamer for ultrasensitive detection of cocaine. Biosensors and Bioelectronics, 73, 245-250 (IF: 7.476)

 

M. Alibolandi, M. Ramezani, K. Abnous, F. Sadeghi, F. Atyabi, M. Asouri, A. A. Ahmadi, F. Hadizadeh (2015). In vitro and in vivo evaluation of therapy targeting epithelial-cell adhesion-molecule aptamers for non-small cell lung cancer. Journal of Controlled Release, 209, 88-100. (IF: 7.441)

 

S. M. Taghdisi, N. M. Danesh, P. Lavaee, A. S. Emrani, M. Ramezani*, K. Abnous (2015). Aptamer Biosensor for Selective and Rapid Determination of Insulin. Analytical Letters, 48 (4), 672-681. (IF: 1.088).

M. Ramezani, N. M. Danesh, P. Lavaee, K. Abnous, S. M. Taghdisi (2015). A novel colorimetric triple-helix molecular switch aptasensor for ultrasensitive detection of tetracycline. Biosensors and Bioelectronics, 70, 181-187 (IF: 7.476)

 

M. Mohammadi, Z. Salmasi, M. Hashemi, F. Mosaffa, K. Abnous, M. Ramezani* (2015). Single-walled carbon nanotubes functionalized with aptamer and piperazine-polyethylenimine derivative for targeted siRNA delivery into breast cancer cells. International Journal of Pharmaceutics, 485, 50-60 (IF: 3.994).

 

M. Alibolandi, M. Ramezani, K. Abnous, F. Sadeghi, F. Hadizadeh (2015). Comparative evaluation of polymersome versus micelle structures as vehicles for the controlled release of drugs. Journal of Nanoparticle Research, 17 (2), 76 (IF:2.101).

 

S. H. Jalalian, S. M. Taghdisi, N. M. Danesh, H. Bakhtiari, P. Lavaee, M. Ramezani*, K. Abnous (2015). Sensitive and fast detection of tetracycline using an aptasensor. Analytical Methods, 7, 2523-25-28 (IF: 1.94).

 

M. Alibolandi, M. Ramezani, F. Sadeghi, K. Abnous, F. Hadizadeh. (2015). Epithelial cell adhesion molecule aptamer conjugated PEG–PLGA nanopolymersomes for targeted delivery of doxorubicin to human breast adenocarcinoma cell line in vitro. International Journal of Pharmaceutics, 479, 241-251 (IF: 3.79).

 

A. Mokhtarzadeh, J. Ezzati Nazhad Dolatabadi, K. Abnous, M. de la Guardia, M. Ramezani* (2015). Nanomaterial-based cocaine aptasensors. Biosensors and Bioelectronics, 68, 95-106 (IF: 6.45).

 

M. Hashemi, H. Parhiz, A. Mokhtarzadeh, S.  M. Tabatabai, S. A Farzad, H. Rezagholizadeh Shirvan, M. Ramezani* (2015). Preparation of Effective and Safe Gene Carriers by Grafting Alkyl Chains to Generation 5 Polypropyleneimine. AAPS PharmSciTech, 16(5), 1002-1012 (IF: 1.776).

 

M. Alibolandi, F. Hadizadeh, F. Vajhedin, K. Abnous, M. Ramezani* (2015). Design and fabrication of an aptasensor for chloramphenicol based on energy transfer of CdTe quantum dots to graphene oxide sheet. Materials Science and Engineering C, 48, 611-619 (IF: 2.736)

 

A. Ziaei, J. Hoppstädter, A. K. KiemerM. Ramezani, Z. Amirghofran, B. Diesel (2015). Inhibitory effects of teuclatriol, a sesquiterpene from Salvia mirzayanii, on nuclear factor-κB activation and expression of inflammatory mediators. Journal of Ethnopharmacology, 160, 94-60. (IF: 2.939).

 

M. R. Razavi, H. Hosseinzadeh, M. Malekian, M. Ramezani, K. Abnous (2014). Evaluation of protein ubiquitylation in heart tissue of rats exposed to diazinon (an organophosphate insecticide) and crocin (an active saffron ingredients): Role of HIF-1α. Drug Res (Stuttg). In press (IF: 0.559).

 

A. Mahmoudi, R. K. Oskuee, M. Ramezani, B. Malaekeh-Nikoue (2014). Preparation and in-vitro transfection efficiency evaluation of modified cationic liposome-polyethyleneimine-plasmid nanocomplexes as a novel gene carrier. Current Drug Delivery, 11 (5), 636-642 (IF: 1.478).

 

M. Alibolandi, K. Abnous, M. Ramezani, H. Hosseinkhani, F. Hadizadeh (2014). Synthesis of AS1411-aptamer-conjugated CdTe quantum dots with high fluorescence strength for probe labeling tumor cells. Journal of Fluorescence, 24, 1519-1529 (IF: 1.667).

 

S. M. Taghdisi, S. Sarreshtehdar Emrani, K. Tabrizian, M. Ramezani, K. Abnous, A. Sarreshtehdar Emrani (2014). Ultrasensitive detection of lead (II) based on fluorescent aptamer-functionalized carbon nanotubes. Environmental Toxicology and Pharmacology, 37 (3), 1236-1242 (IF: 1.862).

 

N. Khaghanzadeh, A. Samiei, M. Ramezani, Z. Mojtahedi, M. Hosseinzadeh, A. Ghaderi (2014). Umbelliprenin induced production of IFN-g, and TNF-a, and reduced of IL-10, IL-4, Foxp3 and TGF-b in a mouse model of lung cancer. Immunopharmacology and immunotoxicology, 36(1), 25-32 (IF: 1.11).

 

H. Hosseinzadeh, S. Mehri, A. Heshmati, A.H. Sahebkar, M. Ramezani, K. Abnous (2014). Proteomics Screening of Molecular Targets of Crocin. DARU Journal of Pharmaceutical Sciences, 22:5 (IF: 1.11).

 

Z. Firouzi, P. Lari, M. Rashedinia, M. Ramezani, M. Iranshahi, K. Abnous (2014). Proteomics screening of molecular targets of curcumin in the mouse brain. Life Sciences 98, 12–17 (IF: 2.30).

 

H. Parhiz and M. Ramezani* (2013). From Rationally-Designed Polymeric and Peptidic Systems to Sophisticated Gene Delivery Nano-vectors. International Journal of Pharmaceutics, 457(1), 237-259 (IF: 3.79).

 

H. Parhiz, F. Memari, S. A. Farzad, M. Hashemi, Z. Salmasi, B. Behnam, M. Ramezani* (2013). Alkylcarboxylate Polyethylenimine-grafted Chitosans as Efficient Gene Vectors with Improved Gene Delivery Activity. Current Nanoscience, 9(6), 717-722 (IF: 1.42).

 

S.M. Taghdisi, N.M. Danesh, A. Sarreshtehdar Emrani, K. Tabrizian, M. Zandkarimi, M.  Ramezani*, K. Abnous (2013). Targeted delivery of Epirubicin to cancer cells by PEGylated A10 aptamer. Journal of Drug Targeting, 21(8), 739-744 (IF: 2.72).

 

S.H. Jalalian, S.M. Taghdisi, N. Shahidi Hamedani, S.A. Kalat, P. Lavaee, M. Zandkarimi, N.  Ghows, M. R. Jaafari, S. Naghibi, N. M. Danesh, M. Ramezani*, K. Abnous (2013). Epirubicin loaded super paramagnetic iron oxide nanoparticle-aptamer bioconjugate for combined colon cancer therapy and imaging in vivo. European Journal of Pharmaceutical Sciences. 50, 191-917 (IF: 3.00).

 

B. Behnam, W. T. Shier, A. Hashem Nia, K. Abnous, M. Ramezani* (2013). Non-covalent functionalization of single-walled carbon nanotubes with modified polyethyleneimines for efficient gene delivery. International Journal of Pharmaceutics, 454, 204-215 (IF: 3.79).

 

N. Shahidi-Hamedani, W. T. Shier, F. Moghadam Ariaee, K. Abnous, M. Ramezani* (2013). Targeted Gene Delivery with Non-covalent Electrostatic Conjugates of Sgc-8c Aptamer and Polyethylenimine. Journal of Gene Medicine, 15, 261-269 (IF: 1.953).

 

H. Parhiz, M. Hashemi, A. Hatefi, W.T. Shier S.A. Farzad, M. Ramezani* (2013). Arginine-rich hydrophobic polyethylenimine: Potent agent with simple components for nucleic acid delivery. International Journal of Biological Macromolecules, 60, 18– 27. (IF: 3.096).

 

F. Soltani, M. Sankian, A. Hatefi, M. Ramezani* (2013). Development of a novel histone H1-based recombinant fusion peptide for targeted non-viral gene delivery. International Journal of Pharmaceutics, 441 (1-2), 307-315 (IF: 3.79).

 

H. Hosseinzadeh, M. Ramezani, H. Shafaei, E. Taghiabadi (2013). Anticonvulsant Effect of Berberis integerrima L. Root Extracts in Mice. Journal of Acupuncture and Meridian Studies, 6 (1), 12-17.

 

H. Parhiz, M. Hashemi, A. Hatefi, W.T. Shier S.A. Farzad, M. Ramezani* (2013). Molecular weight-dependent genetic information transfer with disulfide-linked polyethylenimine-based nonviral vectors. Journal of Biomaterial Applications. 28(1) 112–124 (IF: 2.764).

 

A. Dehshahri, R. Kazemi Oskuee, M. Ramezani* (2012). Plasmid DNA delivery into hepatocytes using a multifunctional nanocarrier based on sugar-conjugated polyethylenimine. Gene Therapy and Molecular Biology, 14, 62-71.

 

A. Mohammadpour, J. Shamsara, S. Nazemi, S. Ghadirzadeh, S. Shahsavand, M. Ramezani* (2013). Evaluation of RANKL/OPG Serum Concentration Ratio as a New Biomarker for Coronary Artery Calcification: A Pilot Study. Thrombosis, (doi: 10.1155/2012/306263).

 

J. Shamsara, A.H. Mohammadpour, J. Behravan, H. Falsoleiman, M. Ramezani* (2012). Pentoxifylline decreases soluble CD40 ligand concentration and CD40 gene expression in coronary artery disease patients. Immunopharmacology and Immunotoxicology 34 (3), 523-529. (IF: 1.11).

 

M. Ramezani, B. Malaekeh-Nikouei, S. Malekzadeh, R. Baghayeripour, M. Malaekeh-Nikouei (2012). The Effect of Lipopolymer Structure on the Transfection Efficiency of Hydrophobic Polyethylenimine-based Cationic Nanoliposomes. Current Nanoscience, 8 (5), 680-684. (IF: 1.42).

 

A. Dehshahri, R.K. Oskuee, W.T. Shier, M. Ramezani* (2012). β-Galactosylated alkyl-oligoamine derivatives of polyethylenimine (PEI) enhanced transfection of plasmid DNA into hepatic cells with reduced toxicity. Current Nanosciences, 8, 548-555. (IF: 1.42).

 

M. Ramezani, R.L. White (2011). Enantioselective catabolism of racemic serine: preparation of d-serine using whole cells of Fusobacterium nucleatum. Tetrahedron Asymmetry  22(13), 1473-1478. (IF: 2.165).

 

J. Motaharinia, M. Ramezani, M. Malaekeh-Nikouei, B. Malaekeh-Nikouei (2011). Liposome-linear polyethyleneimine-DNA nanocomplexes for gene delivery: preparation, characterization and In vitro transfection activity. Current Nanoscience, 7(4), 587-593. (IF: 1.42).

 

M. Ramezani, K. L. Resmer, R.L. White (2011). Glutamate racemization and catabolism in Fusobacterium varium. FEBS Journal, 278, 2540-2551. (IF: 3.986).

 

S. M. Taghdisi, P. Lavaee, M. Ramezani*, and K. Abnous (2011). Reversible targeting and controlled release delivery of daunorubicin to cancer cells by aptamer-wrapped carbon nanotubes. European Journal of Pharmaceutics and Biopharmaceutics, 77, 200-206. (IF: 3.00).

 

M. Hashemi, H. Parhiz, A. Hatefi and M. Ramezani* (2011). Modified polyethylenimine with histidine-lysine short peptides as gene carrier. Cancer Gene Therapy 18(1), 12-19. (IF: 2.553).

 

M. Ramezani, F. Nazemian, J. Shamsara, R. Koohrokhi, A.H. Mohamadpour (2011). Effect of omega-3 fatty acids on plasma level of 8-isoprostane in kidney transplant patients. J. Renal Nutrition. 21(2), 196-199.

 

J. Shamsara, J. Behravan, H. Falsoleiman, A.H. Mohammadpour, J. Rendeirs, M. Ramezani* (2011). Pentoxifylline administration changes protein expression profile of coronary artery disease patients. Gene 487(1), 107-111. (IF: 2.082).

 

J. Behravan, M. Ramezani, E.F. Nobandegani, M.E. Gharaee (2011). Antiviral and antimicrobial activity of Thymus transcaspicus essential oil, Pharmacologyonline, 1, 1190-1199.

 

Z. Salmasi, M. Ramezani, Z.S. Noghabi, J. Behravan (2011). Euphorbia microsciadia percolatio ad Soxhlet extracts exhibit antiviral activity. Pharmacologyonline 1, 910-920.

 

A. Ziaei, M. Ramezani, L. Wright,C. Paetz, B. Schneider, Z. Amirghofran (2011). Identification of spathulenol in Salvia mirzayanii and the immunomodulatory effects. Phytotherapy Research, 25(4), 557-562. (IF: 1.746)

 

H. Hosseinzadeh, J. Behravan, M. Ramezani, S. Sarafraz, E. Taghiabadi (2011). Study of antitumor effect of methanolic and aqueous extracts of Allium sativum L. (Garlic) cloves using potato disc bioassay. Pharmacologyonline, 1, 881-888.

 

R. K. Oskuee, A. Philipp, A. Dehshahri, E. Wagner, M. Ramezani (2010). The impact of carboxyalkylation of branched polyethylenimine on effectiveness in siRNA delivery. Journal of Gene Medicine 12(9), 729-738 (IF: 2.968).

 

J. Behravan, M. Ramezani, H. Alidoost, M.E. Gharaee (2010). Evaluation of anti phage CP51 effect of Euphorbia myrcinites extract by a plaque reduction assay. Pharmacologyonline, 2, 788-797.

 

R. E. Heravi, M. Ramezani, J. Behravan (2010). Association Between Nicotine Metabolism and CYP2A6*1 and CYP2A6*4 Genotypes in an Iranian Population. DNA and Cell Biology, 29(7), 369-373. (IF: 1.988)

Z. Amirghofran, M. Bahmani, A. Azadmehr, K. Javidnia, M. Ramazani, A.Ziaei (2010). Effect of Salvia mirzayanii on the immune system and induction of apoptosis in peripheral blood lymphocytes. Natural Products Research, 24(6), 500-508.

G. Timité, A. Mitaine-Offer, T. Miyamoto, M. Ramezani, A. Rustaiyan, J. Mirjolet, O. Duchamp, M. Lacaille-Dubois (2010). Structure elucidation of new oleanane-type glycosides from three species of Acanthophyllum, Magnetic Resonance in Chemistry, 48(5), 370-374.


M. Ebrahimi, M. Ramezani, S. Omidvar Tehrani, O.M. Malekshah, J. Behravan. (2010). Cytotoxic effect of methanolic extract and essential oil of Artemisia kopetdaghensis. Journal of Essential Oil Bearing Plants, 13(6), 732-737.

 

A. Dehshahri, R. K. Oskuee, W. T. Shier,M. Ramezani (2009). Alkyl acid grafting of polyethylenimine: a simple approach to have a DNA nano-carrier with low toxicity. Journal of Gene Medicine, 11(10), 921-932.

 

R. K. Oskuee, A. Dehshahri, W. T. Shier, A.Hatefi,M. Ramezani (2009). Gene transfer efficiency of high primary amine content, hydrophobic, alkyl-oligoamine derivatives of polyethylenimine . Biomaterials, 30, 4187-4194.

 

M. Ramezani, M. Khoshhamdam, A. Dehshahri, B. Malaekeh-Nikouei (2009). The influence of size, lipid composition and bilayer fluidity of cationic liposomes on the transfection efficiency of nanolipoplexes Colloids and Surfaces B: Biointerfaces, 72, 1-5.

 

B. Malaekeh-Nikouei, M. Malaekeh-Nikouei, R. K. Oskuee, M. Ramezani (2009). Preparation, characterization, transfection efficiency and cytotoxicity of liposomes containing oligoamine-modified cholesterols as nanocarrier to Neuro2A cells. Nanomedicine: Nanotechnology, Biology and Medicine, 5, 457-462.

 

J. Shamsara, M. Ramezani, A. H. Mohammadpour (2009). Why homocysteine-lowering therapy does not have beneficial effects on patients with cardiovascular disease? Bioscience Hypotheses 2, 13-15.

 

M. Nakhaei, M. Khajeh Karamoddin, M. Ramezani (2009). In vitro antibacterial activity of sweet basil fractions against Helicobacter pylori. Journal of Biological Sciences, 9(3), 276-279.

 

S. Kaabinejadian, Sh. Fouladdel, M. Ramezani, and E. Azizi (2008). Molecular Analysis of p53 and MEN1 Expression in MCF7, T47D and MDA-MB 468 Breast Cancer Cell Lines Treated with Adriamycin. Journal of Biological Sciences, 8(2), 380-385.

 

M. Ramezani, J. Behravan, M. Arab, S. Amel Farzad (2008). Antiviral activity of Euphorbia helioscopia extract. Journal of Biological Sciences, 8(4), 809-813.

W. T. Shier,  H. K. Abbas,  R.E. Baird, M. Ramezani, G.L. Sciumbato (2007). (-)-Botryodiplodin, a unique ribose-analog toxin. Toxin Reviews, 26 (4), 343 – 386.

S. Sajadi Tabassi,, M. Ramezani, E. Moghimipour, S. Mohajeri (2007). Isolation, characterization and study of enhancing effects on nasal absorption of insulin in rat of the total saponin from Acanthophyllum squarrosum. Indian J. Pharmacology, 39(5), 226-230.

M. Ramezani, W. T. Shier, H. K. Abbas, J. L. Tonos, R. E. Baird, and G. L. Sciumbato (2007). Soybean Charcoal Rot Disease Fungus Macrophomina phaseolina in Mississippi Produces the Phytotoxin (-)-Botryodiplodin but No Detectable Phaseolinone. Journal of Natural Products, 70(1), 128-129.

 

M. Iranshahi, P. Arfa, M. Ramezani, M. R. Jaafari, H. Sadeghian, C. Bassarello, S. Piacente and C. Pizza (2007). Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes. Phytochemistry, 68(4), 554-561.


J. Behravan, M. Ramezani, M.K. Hassanzadeh, M. Edari, J. Kasaian, Z. Sabeti (2007). Composition, antimycotic and antibacterial activity of Ziziphora clinopodioides Lam. Essential oil from Iran. J. Essential Oil-Bearing Plants, 10(4), 339-345.

 

F. Hadizadeh, A. Moradi, G. Naghibi, M. Vojdani, J. Behravan, M. Ramezani (2007). Synthesis and antitumor activity of substituted succinamides using potato disc tumor induction assay. International Journal of Biomedical Sciences, 3(1), 100-105.

 

J. Behravan, M. Ramezani, M.K. Hassanzadeh, S. Ebadi (2007). Evaluation of antibacterial activity of the essential oils of Zataria multiflora, Carum copticum and Thymus vulgaris by a thin layer chromatography-bioautography method. Journal of Essential Oil-Bearing Plants, 10(3), 259-264.

 

M.R. Jaafari, J. Behravan, J. Abde-Emami, F. Saghafi-Khadem, M. Ramezani (2006). Evaluation of leishmanicidal effect of Euphorbia bungei extract by in vitro antileishmanial assay using promastigote of Leishmania major. International Journal of Pharmacology, 2(5), 571-575.

 

J. Behravan, M. Ramezani, M.K. Hassanzadeh, N. Eliaspour, Z. Sabeti (2006). Cytotoxic and Antimycotic Activities of Essential Oil of Artemisia turanica Krasch from Iran. Journal of Essential Oil-Bearing Plants, 9(2), 196-202.

 

S.A. Sajadi Tabasi, H. Hosseinzadeh, M. Ramezani, E. Moghimipour, S.A. Mohajeri (2006). Isolation, Characterization and Study of Enhancing Effects on Nasal Absorption of Insulin in Rat of the Total Saponin from Acanthophyllum squarrosum. Current Drug Delivery, 3, 399-404.

 

M. Nakhaei, F. Malekzadeh, M. Khaje-Karamoddin, M. Ramezani (2006). In Vitro Anti-Helicobacter pylori Effects of Sweet Basil (Ocimum basilicum L.) and Purple Basil (Ocimum basilicum var purpurascens). Pakistan Journal of Biological Sciences. Pakistan Journal of Biological Sciences. 9(15), 2887-2891.

 

A. Farhat, A. Mohammadzadeh, M. Amiri, M. Ramezani (2006). Effect of Cotoneaster tricolor pojark manna on serum bilirubin levels in neonates. International Journal of Pharmacology. 2(4), 455-458.

 

M. Ramezani, J. Behravan, A. Yazdinejad (2006). Composition and antimicrobial activity of the volatile oil of Artemisia kopetdaghensis from Iran. Flavour and Fragrance Journal. 21(6), 869-871.

 

Karimi G, Ramezani M, Abdi A (2005). Protective effects of lycopene and tomato extract against doxorubicin-induced cardiotoxicity. Phytotherapy Research. 19(10), 912-914.

 

G. Karimi, M. Ramezani, Z. Tahoonian (2005). Cisplatin nephrotoxicity and protection by milk thistle extract in rats. Evidence-based Complementary and Alternative Medicine, 2(3), 383-386.

 

M. Ramezani, J. Behravan, A. Yazdinejad (2004). Composition and antimicrobial activity of the volatile oil of Artemisia khorassanica Podl. from Iran. Pharmaceutical Biology, 42(8), 1-4

 

G. Gaidi, T. Miyamoto, M. Ramezani, M. Lacaille-Dubois (2004). Glandulosides A-D, triterpene saponins from Acanthophyllum glandulosum. J. Natural Products, 67(7), 1114-1118.

 

M. Ramezani, M. Khajeh-Karamoddin, V. Karimi-Fard (2004). Chemical composition and antihelicobacter pylori activity of the essential oil of Pistacia vera L. Pharmaceutical Biology, 42(7), 1-3.

 

M. Haddad, T. Miyamoto, M. Ramezani, M. Lacaille-Dubois (2004). New triterpene saponins from Acanthophyllum pachystegium. Helvetica Chimica Acta 87, 73-81.

 

M. Ramezani, B.S. Fazli-Bazzaz, F. Saghafi-Khadem, A. Dabaghian (2004). Antimicrobial activity of four Artemisia species of Iran. Fitoterapia 75, 201-203.

 

M. Ramezani, H. Hosseinzadeh, S. Samizadeh (2004). Antinociceptive effects of Zataria multiflora Boiss fractions in mice. J. Ethnopharmacol. 91, 167-170.

 

J. Behravan, M. Ramezani, J. Kasaian, Z. Sabeti (2004). Antimycotic activity of the essential oil of Satureja mutica Fisch & C.A. May from Iran. Flavour and Fragrance Journal 19, 421-423.

 

A. Asadipour, M. Ramezani, Y. Amanzadeh (2004). Composition of the volatile oil of Salvia mirzayanii Rech and Esphand from Iran. Journal of essential oil bearing plants, 7(2).

 

H. Hosseinzadeh, M. Ramezani, N. Namjo (2003). Muscle relaxant activity of Elaegnus angustifolia L. fruit seeds in mice. Journal of Ethnopharmacology 84, 275-278.

 

M.H. Boskabady, M. Ramezani, T. Tabei. (2003). Relaxant effects of different fractions of essential oils from Carum copticum on guinea pig tracheal chains. Phytotherapy Research 17, 1145-1149.

 

R. Miri, M. Ramezani, K. Javidnia and L. Ahmadi. (2002). Composition of the volatile oil of Thymus transcaspicus klokov from Iran. Flavor and Fragrance Journal 17 (4), 245-246.

 

M. Ramezani, M.K. Hassanzadeh and D.M. Safdarabadi, (2002). Volatile constituents of Stachys lavandulifolia Vahl. growing in Iran. ACGC Chemical Research Communication 15, 20-24.

 

H. Hosseinzadeh, M. Ramezani and A. Danaei. (2002). Antihyperglycemic effects of Securigera securidaca L. seeds extract in mice. Phytotherapy Research, 16, 1-3.

 

H. Hosseinzadeh, M. Ramezani, M. Fadishei and M. Mahmoudi. (2002). Antinociceptive, anti-inflammatory and acute toxicity effects of Zhumeria  majdae extract in mice and rats. Phytomedicine, 9, 135-141.

 

M. Ramezani, H. Hosseinzadeh, K. Mojtahedi. (2001). Effects of Ferula gummosa Boiss. fractions on morphine dependence in mice. J. Ethnopharmacol., 77, 71-75. 

 

M. Ramezani, H. Hosseinzadeh, N. Daneshmand. (2001). Antinociceptive effects of Elaeagnus angustifolia fruit seed in mice. Fitoterapia, 72, 255-262.

 

H. Hosseinzadeh, M. Ramezani, G. Salmani. (2000). Antinociceptive, anti-inflammatory and acute toxicity effects of Zataria multiflora Boiss extract in mice and rats. J. Ethnopharmacol., 73(3), 379-385.

 

M. K. Hassanzadeh, M. Ramezani, S. Golmohammadzadeh. (2000). Volatile constituents of Nigella sativa L. seeds. J. Oriental Chem. 16(3), 461-462.

 

M. Ramezani, S.E. MacIntosh, and R.L. White, (1999). Utilization of d-Amino Acids by Fusobacterium nucleatum and Fusobacterium varium. J. Amino Acids, 17(2), 185-193.

 

 

b) In National Journals (in english):

 

S. M. Naghibi, M. Ramezani, N. Ayati, S.R. Zakavi (2015). Carum induced hypothyroidism: an interesting observation and an experiment. Daru-Journal of Pharmacetical Sciences, 23(5), doi:10.1186/s40199-015-0094-9 (IF: 1.11).

 

A. H. Mohammadpour, H. Falsoleiman, J. Shamsara, G. Allahabadi, R. Rasooli, M. Ramezani* (2014). Pentoxifylline decreases serum level of adhesion molecules in atherosclerosis patients. Iranian Biomedical Journal 17(4), 23-27.

 

H. Hosseinzadeh, S. Mehri, M.M. Abolhassani, M. Ramezani, A. Sahebkar, Kh. Abnous (2013). Affinity-based target deconvolution of safranal. DARU Journal of Pharmaceutical Sciences 21:25.

 

Z.R. Amin, M. Rahimizadeh, H. Eshghi, A. Dehshahri, M. Ramezani* (2013). The effect of cationic charge density change on transfection efficiency of Polyethylenimine. Iranian Journal of Basic Medical Sciences 16 (2), 150-156.

 

A.H. Mohammadpour, M. Ramezani, A.T. Anaraki, B. Malaekeh-Nikouei, S.A. Farzad, H. Hosseinzadeh (2013).  Development and validation of hplc method for determination of crocetin, a constituent of saffron, in human serum samples. Iranian Journal of Basic Medical Sciences 16 (1), 47-55.

 

N. Khaghanzadeh, Z. Mojtahedi, M. Ramezani, N. Erfani, A. Ghaderi (2012). Umbelliprenin is cytotoxic against QU-DB large cell lung cancer cell line but anti-proliferative against A549 adenocarcinoma cells. DARU, Journal of Pharmaceutical Sciences 20(1), 69.

 

N. Fazel, M. Hashemian, M. Ramezani, A. Akaberi (2012). Comparative effect alone honey and mix with chlotrimazol on vaginitis candidacies. Iranian Journal of Obstetrics, Gynecology and Infertility 14(8).

 

J. Shamsara, J. Behravan, H. Falsoleiman, A.H. Mohammadpour, M. Ramezani* (2012). The effects of pentoxifylline administration on NFKB P50 transcription factor expression. ARYA Atherosclerosis 7(4), 133-137.

 

H. Hosseinzadeh, M. Ramezani, Z. Afarin (2012). Effect of Ocimum basilicum L. aerial parts extract and fractions on morphine withdrawal syndrome in mice. Journal of Medicinal Plants 11 (SUPPL. 8), 227-238.

A. Ziaei, Z. Amirghofran, J. Zapp, M. Ramezani* (2011). Immunoinhibitory effect of teuclatriol a guaiane sesquiterpene from Salvia mirzayanii. Iranian Journal of Immunology 8 (4), 226-235.

M. Ramezani, B. Malaekeh-Nikouei, T. Khakshoor, M. Malaekeh-Nikouei (2011). The effect of linear PEI on characteristics and transfection efficiency of PEI-based cationic nanoliposomes. Iranian Journal of Basic Medical Sciences, 14(1), 82-88.

 

 

امتیاز کاربران

ستاره غیر فعالستاره غیر فعالستاره غیر فعالستاره غیر فعالستاره غیر فعال

 

 

Mahmoud Reza Jaafari

 

 

Professor of Pharmaceutics and Pharmaceutical Nanotechnology,

 

        [at]mums.ac.ir
[at]yahoo.com

 

Address: Nanotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

Phone: +98 513 8823255 (Office), +98 513 7619770 (Home)

Mobile: +98 915 3164001; Fax: +98 513 8823251

E-mail: این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید or این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید;

Website: http://www.mums.ac.ir/pharmacy/fa/drjaafari

Updated at:   6/28/2016                                                    

                                                       und Educational Background 

Pharm.D.: School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran, 1983-1988

Ph.D. in Pharmaceutics (Nanoliposomal drug and protein delivery): College of Graduate Studies and Research, Division of Pharmaceutical Sciences, University of Saskatchewan, Saskatoon, Canada, 1993-1998

Ph.D. Theses Title: Targeted drug delivery based on adhesion domains of immunoglobulin superfamily: P0 protein as a model

 

Visiting Associate Professor: Department of Biopharmaceutical Sciences and Pharmceutical Chemistry; School of Pharmacy, University of California at San Francisco (UCSF), 2006-2007 (Pharmaceutical Nanotechnology).

 

                                                                   Research Interests

Research Interests: Targeted drug delivery, nanomedicine, liposomal drug delivery, cancer treatment using nanoliposomes containing cytotoxic drugs, topical liposomes for the treatment of leishmaniasis, liposome based vaccination against cancer and leishmaniasis, liposome based nucleic acid delivery, peptide and protein formulation.

 

                                                                       Publications

1)      Foldvari M., Jaafari M.R., Mezei C., and Mezei M. (1998) Targeting of liposomes through immunoglobulin superfamily domains: P0 protein as a model. Drug Delivery, 5: 183-195.

2)      Jaafari M.R. and Foldvari M. (1999) P0 protein mediated targeting of liposomes to melanoma cells with high level of ICAM-1 expression. J. Drug Targeting, 7: 101-112.

3)      Jaafari M.R. and Foldvari M. (2002) Targeting of liposomes to human keratinocytes through adhesive peptides from immunoglobulin domains in the presence of IFN-gamma. Drug Delivery, 9:

4)      Jaafari M.R. and Foldvari M. (2002) Targeting of liposomes to melanoma cells with high level of ICAM-1 expression through adhesive peptides from immunoglobulin domains. J. Pharm.Sci. 91: 396-404.

5) Tafaghodi M., Sajadi Tabassi S.A., Jaafari M.R., (2004), Evaluation of the clearance characteristics of various microspheres in the human nose by gamma-scintigraphy. Int. J. Pharmaceutics, 280: 125-135.

6) Balali Mood M., Hefazi M., Mahmoudi M., Jalali I., Attaran D., Maleki M.,   Etezad Razavi M.R., Zare G., Jaafari M.R., Tabatabaee A., (2005) Evaluation of delayed toxic effects of sulfur mustard poisoning in severely intoxicated iranian veterans: A cross sectional study. Journal of Medical Chemical, Boilogical and Radiological Defense, 3: 1-32.

7) Sohrabi Y., Jaafari M.R., Miramin Mohammadi A., Eskandari S.E., Khamesipour A., (2004), Induction of cell mediated immunity against leishmaniasis using mannan coated liposomes encapsulated with autoclaved Leishmania major (ALM), International Proceeding Immunology, 125-128.

8) Foldvari M., Jaafari M.R., Radhi J., Segal D., (2005) Efficacy of the anti-adhesin, 2-O-propyl-octyl -Gal NAc (1-4) -Gal (Fimbrigal-P), in a rat oral candidiasis model. Antimicrob. Agents Chemother. 49:  2887-2894.

9) Balali-Mood M, Hefazi M, Mahmoudi M, Jalali E, Attaran D, Maleki M, Razavi ME, Zare G, Tabatabaee A, Jaafari MR. (2005) Long-term complications of sulphur mustard poisoning in severely intoxicated Iranian veterans. Fundam Clin Pharmacol. 19 (6): 713-21.

10) Tafaghodi M., Sajadi Tabassi S.A., Jaafari M.R., (2006), Formulation, characterization and release studies of alginate microsphere encapsulated with tetanus toxoid. J. Biomater. Sci. Polymer Edn, 17 (8): 909-924.

11) Malaekeh-Nikouei B., Sajadi Tabassi S. A., Jaafari M. R. (2006) The Effect of Different Grades of PLGA on Characteristics of Microspheres Encapsulated with Cyclosporine A., Curr Drug Deliv. 2006 Oct; 3(4):343-9.

12) Jaafari M.R., Attieh Ghafarian A.,Farrokh-Gisour A., Samiei A., Tavassoti Kheiri M., Mahboudi F., Barkhordari F., Khamesipour A., McMaster W.R. (2006)Immune response and protection assay of recombinant major surface glycoprotein of Leishmania (rgp63) reconstituted with liposomes in BALB/c mice, Vaccine, 24: 5708-5717.

13) Tafaghodi M., Sajadi Tabassi S.A., Jaafari M.R., (2006), Induction of systemic and mucosal immune responses by intranasal administration of alginate microspheres encapsulated with tetanous toxoid and CpG-ODN. Int. J. Pharm. 319: 37-43.

14) Malaekeh-Nikouei B., Sajadi Tabassi  S. A., Jaafari, M. R., Davies N. M., The effect of complexation on characteristics and drug release of PLGA microspheres loaded by cyclosporine-cyclodextrin complex, Journal of Drug Delivery Science and Technology, September/November 2006, 16 (5): 345-350.

15) Tafaghodi M., Jaafari M.R., Sajadi Tabassi S.A., (2006), Nasal immunization studies using liposomes loaded with tetanous toxoid and CpG-ODN. Eur. J. Pharm. Biopharm 64: 138-145.

16) Tabbakhian M., Tavakoli N., Jaafari M.R., Daneshamouz S., (2006) Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes: 1. In Vitro Permeation and In Vivo Deposition Studies Using Hamster Flank and Ear Models, Int. J. Pharm. 323: 1-10.

17) M. R.  Jaafari, J. Behravan, J. Abde-Emami, F. Saghafi-Khadem,  M. Ramezani , (2006), Evaluation of leishmanicidal effect of Euphorbia bunjei extract by in vitro leishmanicidal assay using promastigote of Leishmania major, Int. J. Pharmacology 2 (5): 571-575.

18) Badiee A, Jaafari MR, Khamesipour A. (2007) Leishmania major: Immune response in BALB/c mice immunized with stress-inducible protein 1 encapsulated in liposomes. Exp. Parasitol. 115(2): 127-134.

19) Iranshahi M, Arfa P, Ramezani M, Jaafari MR, Sadeghian H, Bassarello C, Piacente S, Pizza C. (2007) Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes.

Phytochemistry. 2007 Feb; 68 (4): 554-61.

20) Jaafari M.R., Badiee A., Khamesipour A., Samiei A., Soroush D., Tavassoti Kheiri MT., Barkhordari F., McMaster W.R., Mahboudi F. (2007)The role of CpG ODN in enhancement of immune response and protection in BALB/c mice immunized with recombinant major surface glycoprotein of Leishmania (rgp63) encapsulated in cationic liposome, Vaccine 25: 6107-6117 (2007).
21) Jaafari M.R., Hooshmand S., Samiei A., Hossainzadeh H., (2007), Evaluation of leishmaniacidal effect of Perovskia abrotanoides Karel root extract by in vitro leishmanicidal assay using promastigotes of Leishmania major, Pharmacologyonline 1: 299-303.
22) Monajjemi M., Afsharnezhad S., Jaafari M.R., Abdolahi T., Nikosade A., Monajemi H., (2007), NMR shielding and a thermodynamic study of the effect of environmental exposure to petrochemical solvent on DPPC, an important component of lung surfactant, Russian Journal of Physical Chemistry A, 81(12): 1956-1963.
23) Malaekeh-Nikouei B., Jaafari M. R., Sajadi Tabassi S. A., (2007) Preparation, characterization and mucoadhesive evaluation of chitosan coated liposomes containing cyclosporine A. Saudi Pharmaceutical Journal, 15 (3-4): 176-182.
24) Vahdati-Mashhadian N., Jaafari M.R., Nosrati A., (2007), Differential toxicity of rifampin on HEPG2 and HEP2 cells using MTT test and electron microscope. Pharmacologyonline 3: 405-413.
25) Monajjemi M., Afsharnezhad S., Jaafari M.R., Mirdamadi S, Mollaamin F., Monajemi H., (2008), Investigation of energy and NMR isotropic shift on the internal rotation barrier of O4 dihedral angle of the DLPC: A GIAO study, Chemistry 17 ( 1): 55-69.
 
26) Monajjemi M., Afsharnezhad S., Jaafari M.R., Mirdamadi S., Monajemi H., Mollaamin F., (2008), Theoretica study of solvent effects and NMR shielding tensors of DLPC,  Indonesian Journal of Chemistry 8 (1): 58-64.

27) Badiee A, Jaafari MR, Samiei A, Soroush D, Khamesipour A. Coencapsulation of CpG oligodeoxynucleotides with recombinant Leishmania major stress-inducible protein 1 in liposome enhances immune response and protection against leishmaniasis in immunized BALB/c mice. Clin Vaccine Immunol. 2008 Apr;15(4):668-74.

28) Tafaghodi M., Jaafari M.R., Sajadi Tabassi S.A., (2008) Nasal immunization studies by cationic, fusogenic and cationic-fusogenic liposomes encapsulated with tetanous toxoid, Curr Drug Deliv. 5(2); 108-113.

29) Malaekeh-Nikouei B, Sajadi Tabassi SA, Jaafari MR. (2008 May) Preparation, characterization, and mucoadhesive properties of chitosan-coated microspheres encapsulated with cyclosporine a. Drug Dev Ind Pharm. 34 (5): 492-8.

30) Sajadi Tabassi S.A., Tafaghodi M., Jaafari M.R., (2008) Induction of high antitoxin titers against tetanous toxoid in rabbits by intranasal immunization with dextran microspheres, Int. J. Pharm. 2008 Aug 6;360(1-2):12-7.

31) Golmohammadzadeh S., Jaafari M.R., Khalili N., (2008) Evaluation of liposomal and conventional formulations on the human percutaneous absorption of octyl methoxycinnamate using stripping method. Journal of Cosmetic Science 59 (5): 385-398.

32) Malaekeh-Nikouei B., Jaafari M. R., Sajadi Tabassi S. A., Samiei A., (2008) The Enhancement of Immunosuppressive Effects of Cyclosporine A on Human T-Cells Using Fusogenic Liposomes, Colloids and Surface B: biointerfaces, 67: 238-244.

33) Hosseinzadeh H, Jaafari MR, Shamsara J. Selective inhibitory effect of adenosine A1 receptor agonists on the Selective inhibitory effect of adenosine A1 receptor agonists on the proliferation of human tumor cell lines. Iran Biomed J. 2008 Oct; 12(4):203-8.

34) Badiee A., Jaafari M.R., Khamesipour A., Samiei A., Soroush D., Tavassoti Kheiri M., Barkhordari F., McMaster W.R., Mahboudi F. (April 2009)The role of liposome charge on immune response generated in BALB/c mice immunized with recombinant major surface glycoprotein of Leishmania (rgp63), Exp. Parasitol. 121 (4): 362-9.

35) Razzazan A, Saberi MR, Jaafari MR. (2008) Insights from the analysis of a predicted model of gp63 in Leishmania donovani. Bioinformation. 3 (3): 114-8.

36) Jaafari M.R., Bavarsad N, Fazly Bazzaz B.S., Samiei A., Dina Soroush,Ghorbani S., Lotfi Heravi M.M., Khamesipour A. (June 2009) The Effect of Topical Liposomes Containing Paromomycin Sulfate (PM) in the Course of Leishmania major Infection in Susceptible BALB/c Mice. Antimicrob. Agents Chemother. 53 (6): 2259-2265.

37) Abrishami M, Ganavati SZ, Soroush D, Rouhbakhsh M, Jaafari MR, Malaekeh-Nikouei B. Preparation, characterization, and in vivo evaluation of nanoliposomes-encapsulated bevacizumab (avastin) for intravitreal administration. Retina. 2009 May;29(5):699-703

38) Huang Z, Jaafari MR, Szoka FC Jr. 2009, Disterolphospholipids: Nonexchangeable Lipids and Their Application to Liposomal Drug Delivery. Angew Chem Int Ed  48: 4146-4149.

39) Badiee A, Jaafari MR, Khamesipour A, Samiei A, Soroush D, Kheiri MT, Barkhordari F, McMaster WR, Mahboudi F. (2009) Enhancement of immune response and protection in BALB/c mice immunized with liposomal recombinant major surface glycoprotein of Leishmania (rgp63): The role of bilayer composition. Colloids Surf B Biointerfaces. 74: 37-44.

40) Hadizadeh F, Moallem SA, Jaafari MR, Shahab M, Alahyari M, Rameshrad M, Samiei A. (2009) Synthesis and immunomodulation of human lymphocyte proliferation and cytokine (interferon-gamma) production of four novel malonitrilamides. Chem Biol Drug Des. 73(6):668-73.

41) Amin M, Jaafari MR, Tafaghodi M. (2009) Impact of chitosan coating of anionic liposomes on clearance rate, mucosal and systemic immune responses following nasal administration in rabbits. Colloids Surf B Biointerfaces. 74: 225-229.

42) Ebrahimnejad P, Dinarvand R, Sajadi SA, Atyabi F. Ramezani F, Jaafari MR, 2009, Preparation and Characterization of Poly Lactide-co-glycolide Nanoparticles of SN-38. PDA J. Pharm. Sci. Technol. 63: 512-520.

43) Ebrahimnejad P, Dinarvand R, Sajadi SA, Jaafari MR, Movaghari F, Atyabi F,  2009, Development and Validation of an Ion-pair HPLC Chromatography for Simultaneous Determination of Lactone and Carboxylate Forms of SN-38 in Nanoparticles. Journal of Food and Drug Analysis, 17 (4): 246-256.

44) Raji AR, Jaafari MR, 2009, Transmission electron microscopy study of the alveolar septum in adult camel, Indian Veterinary Journal, 86 (7): 719-721.

45) Hejazi H, Tasbihi M, Jaafari MR, Badiee A, Pestechian N, A Javadi A, Khamesipour A, 2010, The Role of Liposomal CpG ODN on the Course of L. major Infection in BALB/C Mice, Iranian J. Parasitol. 5 (1): 47-54.

46) Ebrahimnejad P, Dinarvand R, Sajadi A, Jaafari MR, Nomani AR, Azizi E, Rad-Malekshahi M, Atyabi F. (2010 June), Preparation and in vitro evaluation of actively targetable nanoparticles for SN-38 delivery against HT29 cell lines. Nanomedicine. 6 (3): 478-85.

47) Tafaghodi M., Khamesipour A., Jaafari M.R. (Dec. 2010), Immunization against leishmaniasis by PLGA nanospheres loaded with an experimental Autoclaved Leishmania major (ALM) and Quillaja saponins, Tropical Biomedicine 27(3): 639–650.

48) Tafaghodi M., Khamesipour A., Jaafari M.R., (2011 May), Immunization against leishmaniasis by PLGA nanospheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN, Parasitol Res. 108(5):1265-1273.

49) F. Vahedi, M.R. Jaafari, M.R. Mahmoudi, M. (Dec. 2010) The Effect of Using Cationic Liposomes Encapsulating pcDNA3.1+PA Plasmids on Humoral Immune Response in Mice, Iranian Journal of Immunology 7 (4): 210-216.

50) Iman M, Huang Z, Szoka FC, Jaafari MR, (2011 April 15), Characterization of the Colloidal Properties, In vitro Antifungal Activity, Antileishmanial Activity and Toxicity in Mice of a Distigmasterylhemisuccinoyl-glycero-phosphocholine Liposome-Intercalated Amphotericin B. Int J Pharm. 408(1-2):163-72.

51) Ebrahimnejad P, Dinarvand R, Jaafari MR, Sajadi SA, Atyabi F. (2011 Mar 15),  Characterization, blood profile and biodistribution properties of surface modified PLGA nanoparticles of SN-38. Int J Pharm. 406 (1-2): 122-7.

52) Tafaghodi M, Eskandari M, Khamesipour A, Jaafari MR (October 2011), Alginate microspheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN induced partial protection and enhanced immune response against murine model of leishmaniasis. Exp Parasitol. 129 (2): 107-14.

53) Jalali SA, Sankian M, Tavakkol-Afshari J, Jaafari MR.  (July 2012), Induction of tumor-specific immunity by multi-epitope rat HER2/neu-derived peptides encapsulated in LPD Nanoparticles. Nanomedicine: NBM,  8 (5): 692-701.

54) Pouran Layegh, Omid Rajabi, Mahmoud R. Jaafari, Parisa Emamgholi Tabar Malekshah, Toktam Moghiman, Hamee Ashraf, Roshanak Salari (2011) Efficacy of Topical Liposomal Amphotericin B versus Intralesional Meglumine Antimoniate (Glucantime) in the Treatment of Cutaneous Leishmaniasis. Journal of Parasitology Research, vol. 2011, Article ID 656523, 5 pages, 2011. doi:10.1155/2011/656523.

55) Shiva Golmohammadzadeh, Fatemeh Imani, Hossein Hosseinzadeh, Mahmoud Reza Jaafari (Nov-Dec 2011), Preparation, Characterization and Evaluation of Sun Protective and Moisturizing Effects of Nanoliposomes Containing Safranal. Iranian Journal of Basic Medical Sciences, 14 (6): 521-533.

56) Heravi Shargh V, Jaafari MR, Khamesipour A, Jalali SA, Firouzmand H, Abbasi A, Badiee A. (July 2012) Cationic liposomes containing soluble Leishmania antigens (SLA) plus CpG ODNs induce protection against murine model of leishmaniasis. Parasitol Res. 111(1): 105-114.

57) Adeli, M., Hakimpour, F., Sagvand, M., Jaafari, M.R., Kabiri, R., Moshari, Z. (2011) Supramolecular hybrid nanomaterials as drug delivery systems. Supramolecular Chemistry 23 (6) 411-418.

58) Shargh VH, Jaafari MR, Khamesipour A, Jaafari I, Jalali SA, Abbasi A, Badiee A. (June 6, 2012) Liposomal SLA co-incorporated with PO CpG ODNs or PS CpG ODNs induce the same protection against the murine model of leishmaniasis. Vaccine. 30 (26); 3957-64.

59) Fateme Hoseinipoor, Mahnaz Banihashemi, Mahmoud Reza Jaafari, ZariJavidi, Amir AbasAzarian,Vahid Mashayekhi Goyonlo, (2011) The Effect of Sun Radiation on the Course of Cutaneous Leishmaniasis in BALB/c Mice Iranian Journal of Basic Medical Sciences Vol. 14, No. 2 Mar-Apr 2011, 145-150.

60) Ali Khamesipour, Azam Abbasi, Alireza Firooz, Akram Mir Amin Mohammadi, Seyed Ebrahim Eskandari, Mahmoud R. Jaafari (March-April 2012) Treatment of Cutaneous Lesion of 20 Years’ Duration Caused By Leishmanization. Indian Journal of Dermatology 57(2): 148-150.

61)  Alavizadeh H, Badiee A, Khamesipour A, Jalali SA, Firouzmand H, Abbasi A, Jaafari MR. (Nov. 2012) The role of LPD nanoparticles containing CpG ODN in the course of infection induced by L. major in BALB/c mice. Exp Parasitol. 132: 313-319.

62) Bavarsad N, Bazzaz BS, Khamesipour A, Jaafari MR (2012 Oct) Colloidal, in vitro and in vivo anti-leishmanial properties of transfersomes containing paromomycin sulfate in susceptible BALB/c mice.  Acta Trop. 124 (1): 33-41. Epub 2012 Jun 29.

63) Badiee A, Khamesipour A, Samiei A, Soroush D, Shargh VH, Kheiri MT, Barkhordari F, Robert Mc Master W, Mahboudi F, Jaafari MR. 2012 Sep 13.The role of liposome size on the type of immune response induced in BALB/c mice against leishmaniasis: rgp63 as a model antigen. Exp Parasitol. 132: 403-409.  pii: S0014-4894(12)00261-5. doi: 10.1016/j.exppara.2012.09.001. [Epub ahead of print].

64) Ensieh Golali, Mahmoud Reza Jaafari, Ali Khamesipour, Azam Abbasi, Zahra Saberi, Ali Badiee (Sept. 2012) Comparison of in vivo Adjuvanticity of Liposomal PO CpG ODN with Liposomal PS CpG ODN: Soluble Leishmania Antigens as a Model. Iran J Basic Med Sci. 15 (5): 1032-1045.

65) Badiee A. Shargh VH, Khamesipour A, Jaafari MR, 2013 Jan 21, Micro/Nanoparticle adjuvants for antileishmanial vaccines: present and future trends. Vaccine. 31(5):735-49. doi: 10.1016/j.vaccine.2012.11.068. Epub 2012 Dec 7. Review.

66) Rastgoo M, Hosseinzadeh H, Alavizadeh H, Abbasi A, Ayati Z, Jaafari MR. (2013 Apr) Antitumor Activity of PEGylated Nanoliposomes Containing Crocin in Mice Bearing C26 Colon Carcinoma. Planta Med.79(6):447-51. doi: 10.1055/s-0032-1328363. Epub 2013 Mar 28.

67) Mosallaei N, Jaafari MR, Hanafi-Bojd MY, Golmohammadzadeh S, Malaekeh-Nikouei B, (June 2013) Docetaxel-loaded solid lipid nanoparticles: Preparation, characterization, in vitro, and in vivo evaluations. J Pharm Sci.; 102(6):1994-2004. doi: 10.1002/jps.23522. Epub 2013 Apr 5.

68) Hesamoddin Hoseinjani, Mahmoud Reza Jaafari, Ali Khamesipour, Azam Abbasi, Zahra Saberi, Ali Badiee, (2013) Evaluation of infection course in mice induced by L. major in presence of positively charged liposomes containing CpG ODN. Nanomed. J. 1(1): 30-40.

69) Pouran Layegh, Navid Mosallaei, Danial Bagheri, Mahmoud Reza Jaafari, Shiva Golmohammadzadeh, (2013) The efficacy of Isotretinoin-loaded solid lipid nanoparticles in comparison to Isotrex® on acne treatment . Nanomed. J. 1(1): 41-51.

70) Shiva Golmohammadzadeh, Mohsen Mokhtari, Mahmoud Reza Jaafari, (2012) Preparation, characterization and evaluation of moisturizing and UV protecting effects of topical solid lipid nanoparticles. Brazilian Journal of Pharmaceutical Sciences 48 (4): 683-690.

71) Shiva Golmohammadzadeh, Mohsen Mokhtari, Mahmoud Reza Jaafari, (2012) Improved photostability, reduced skin permeation and irritation of isotretinoin by solid lipid nanoparticles. Acta Pharm. 62: 547–562 DOI: 10.2478/v10007-012-0032-z.

72) Jalalian SH, Taghdisi SM, Shahidi Hamedani N, Kalat SA, Lavaee P, Zandkarimi M, Ghows N, Jaafari MR, Naghibi S, Danesh NM, Ramezani M, Abnous K. 2013 Oct 9, Epirubicin loaded super paramagnetic iron oxide nanoparticle-aptamer bioconjugate for combined colon cancer therapy and imaging in vivo. Eur J Pharm Sci. 50(2):191-7. doi: 10.1016/j.ejps.2013.06.015. Epub 2013 Jul 5.

73) Oskuee RK, Jaafari MR, Amel Farzad S, Ramezani M (June, 2012) In vitro leishmanicidal activity of Calotropis gigantea and its fractions against Leishmania major. Journal of Medicinal Plants Research  6 (23): 3977-3983. DOI: 10.5897/JMPR011.1530

74) Nasser Vahdati-Mashhadian, Mahmoud Reza Jaafari, Nasim Sharghi,  Toktam Sanati (2013) Protective Effects of Vitamin C and NAC on the Toxicity of Rifampin on Hepg2 Cells. Iranian Journal of Pharmaceutical Research. 12 (1): 141-146.

75) Hamid Mohammadpanah, Hossein Rastegar, Mohammad Reza Ramazani and Mahmoud Reza Jaafari, June 2013, Effects of Different Buffers and pH on the Stability of Recombinant Human Growth Hormone, BIOSCIENCES BIOTECHNOLOGY RESEARCH ASIA. Vol. 10(1), 193-203.

76) Firouzmand H, Badiee A, Khamesipour A, Heravi Shargh V, Alavizadeh SH, Abbasi A, Jaafari MR. Dec. 2013, Induction of protection against leishmaniasis in susceptible BALB/c mice using simple DOTAP cationic nanoliposomes containing soluble Leishmania antigen (SLA).  Acta Trop. 128(3): 528-35. doi: 10.1016/j.actatropica.2013.07.021. Epub 2013 Aug 2.

77) Amin M, Badiee A, Jaafari MR. 2013 Dec 31, Improvement of pharmacokinetic and antitumor activity of PEGylated liposomal doxorubicin by targeting with N-methylated cyclic RGD peptide in mice bearing C-26 colon carcinomas. Int J Pharm. 458(2): 324-33. doi: 10.1016/j.ijpharm.2013.10.018. Epub 2013 Oct 19.

78) Chavoshian O, Biari N, Badiee A, Khamesipour A, Abbasi A, Saberi Z, Jalali SA, Jaafari MR. Sphingomyelin Liposomes Containing Soluble Leishmania major antigens Induced Strong Th2 Immune Response in BALB/c Mice. Iran J Basic Med Sci. 2013 Sep; 16 (9):965-72.

79) Jabini R, Jaafari MR, Vahdati Hasani F, Ghazizadeh F, Khamesipour A, Karimi G. March 2015, Effects of Combined Therapy with Silymarin and Glucantime on Leishmaniasis Induced by Leishmania major in BALB/c Mice. Drug Res. 65 (3): 119-124.

80) Shariat S, Badiee A, Jaafari MR, Mortazavi SA. 2014 Winter, Optimization of a Method to Prepare Liposomes Containing HER2/Neu- Derived Peptide as a Vaccine Delivery System for Breast Cancer. Iran J Pharm Res. 2014 Winter; 13(Suppl): 15-25.

81) Moosavian Kalat SA, Khamesipour A, Bavarsad N, Fallah M, Khashayarmanesh Z, Feizi E, Neghabi K, Abbasi A, Jaafari MR. 2014 Aug, Use of topical liposomes containing meglumine antimoniate (Glucantime) for the treatment of L. major lesion in BALB/c mice. Exp Parasitol. 143:5-10. doi: 10.1016/j.exppara.2014.04.013. Epub 2014 Apr 26.

82) Alavizadeh SH, Badiee A, Golmohammadzadeh S, Jaafari MR, 2014 Oct 1, The influence of phospholipid on the physicochemical properties and anti-tumor efficacy of liposomes encapsulating cisplatin in mice bearing C26 colon carcinoma. Int J Pharm. 473(1-2): 326-33. doi: 10.1016/j.ijpharm.2014.07.020. Epub 2014 Jul 19.

83) Reza Kazemi Oskuee, Mahmoud Reza Jaafari, Sara Amani, Mohammad Ramezani (July 2014) Evaluation of leishmanicidal Effect of Euphorbia erythadenia extract by in vitro leshmanicidal assay using Promastigotes of Leishmania major. Asian Pac J Trop Biomed 2014; 4(Suppl 2): S905-S907.

84) Eskandari F, Talesh GA, Parooie M, Jaafari MR, Khamesipour A, Saberi Z, Abbasi A, Badiee A. Immunnoliposomes containing Soluble Leishmania Antigens (SLA) as a novel antigen delivery system in murine model of leishmaniasis. Exp Parasitol. 2014 Sep 19. pii: S0014-4894(14)00206-9. doi: 10.1016/j.exppara.2014.08.016. [Epub ahead of print].

85) Shariat S, Badiee A, Jalali SA, Mansourian M, Yazdani M, Mortazavi SA, Jaafari MR. 2014 Dec 1, P5 HER2/neu-derived peptide conjugated to liposomes containing MPL adjuvant as an effective prophylactic vaccine formulation for breast cancer. Cancer Lett. Cancer Lett. 355(1): 54-60. doi: 10.1016/j.canlet.2014.09.016. Epub 2014 Sep 16.

86) Sahebkar A, Badiee A, Ghayour-Mobarhan M, Goldouzian SR, Jaafari MR. 2014 Oct 1, A simple and effective approach for the treatment of dyslipidemia using anionic nanoliposomes. Colloids Surf B Biointerfaces.;122: 645-52. doi: 10.1016/j.colsurfb.2014.07.045. Epub 2014 Aug 12.

87) Mansourian M, Badiee A, Jalali SA, Shariat S, Yazdani M, Amin M, Jaafari MR. (Nov., 2014) Effective induction of anti-tumor immunity using p5 HER-2/neu derived peptide encapsulated in fusogenic DOTAP cationic liposomes co-administrated with CpG-ODN. Immunol Lett. 162 (1): 87-93.

88) A. Kazemi-Beydokhti, S. Zeinali Heris, M. R. Jaafari, S. Nikoofal-Sahlabadi,  M. Tafaghodi2, M. Hatamipoor, Dec. 2014,  Microwave functionalized single-walled carbon nanotube as nanocarrier for the delivery of anticancer drug cisplatin: in vitro and in vivo evaluation,  J. DRUG DEL. SCI. TECH., 24 (6) 572-578.

89) Hanafi-Bojd MY, Jaafari MR, Ramezanian N, Xue M, Amin M, Shahtahmasbi N, Malaekeh-Nikouei B. (Jan. 2015) Surface functionalized mesoporous silica nanoparticles as an effective carrier for epirubicin delivery to cancer cells. Eur J Pharm Biopharm. 89: 248-258. doi: 10.1016/j.ejpb.2014.12.009. Epub 2014 Dec 13.

90) Khameneh B, Halimi V, Jaafari MR, Golmohammadzadeh S. 2015 Jan, Safranal-loaded solid lipid nanoparticles: evaluation of sunscreen and moisturizing potential for topical applications. Iran J Basic Med Sci. 18(1):58-63.

91) Sahebkar A, Badiee A, Hatamipour M, Ghayour-Mobarhan M, Jaafari MR. (2015 Mar 7), Apolipoprotein B-100-targeted negatively charged nanoliposomes for the treatment of dyslipidemia. Colloids Surf B Biointerfaces.129: 71-78. doi: 10.1016/j.colsurfb.2015.03.012. [Epub ahead of print].

92) Amin Kazemi-Beydokhti, S. Zeinali Heris, M.R. Jaafari (2015) Experimental investigation of thermal conductivity of medical nanofluids based on functionalised single-wall carbon nanotube and conjugated cisplatin, Micro & Nano Letters, 10 (5): 241-247. doi: 10.1049/mnl.2014.0593.

93) Nourbakhsh M, Jaafari MR, Lage H, Abnous K, Mosaffa F, Badiee A, Behravan J., 2015 Apr; Nanolipoparticles-mediated MDR1 siRNA delivery reduces doxorubicin resistance in breast cancer cells and silences MDR1 expression in xenograft model of human breast cancer. Iran J Basic Med Sci. 18(4):385-92.

94) Nourbakhsh M, Behravan J, Lage H, Abnous K, Mosaffa F, Badiee A, Jaafari MR, Winter 2015, Nanolipoparticles-mediated MDR1 siRNA delivery: preparation, characterization and cellular uptake. Nanomedicine Journal. 2(1): 39-45.

95) Nouri HR, Varasteh A, Jaafari MR, Davies JM, Sankian M., 2015 Jul; Induction of a Th1 immune response and suppression of IgE via immunotherapy with a recombinant hybrid molecule encapsulated in liposome-protamine-DNA nanoparticles in a model of experimental allergy. Immunol Res. 62(3): 280-91. doi: 10.1007/s12026-015-8659-8

 

96) Shariat Sh, Badiee A, Jalali SA, Mansourian M, Mortazavi SA, Jaafari MR. 2015 Preparation and characterization of different liposomal formulations containing P5 HER2/neu-derived peptide and evaluation of their immunological responses and antitumor effects. Iran J Basic Med Sci. 18 (5):506-513.

97) Khameneh B, Jaafari MR, Hassanzadeh-Khayyat M, Varasteh A, Chamani J, Iranshahi M, Mohammadpanah H, Abnous K, Saberi MR. 2015 Sep; Preparation, characterization and molecular modeling of PEGylated human growth hormone with agonist activity. Int J Biol Macromol. 80:400-9. doi: 10.1016/j.ijbiomac.2015.06.037. Epub 2015 Jun 23.

98) Banihashemi M, Zabolinejad N, Jaafari MR, Salehi M, Jabari A. 2015 Sep; Comparison of therapeutic effects of liposomal Tranexamic Acid and conventional Hydroquinone on melasma. J Cosmet Dermatol. 14(3):174-7. doi: 10.1111/jocd.12152.

99) Moosavian SA, Jaafari MR, Taghdisi SM, Mosaffa F, Badiee A, Abnous K. 2015 Jun; Development of RNA aptamers as molecular probes for HER2(+) breast cancer study using cell-SELEX. Iran J Basic Med Sci. 18(6):576-86.

100) Teymouri M, Farzaneh H, Badiee A, Golmohammadzadeh S, Sadri K, Jaafari MR. 2015 Dec 1; Investigation of Hexadecylphosphocholine (miltefosine) usage in Pegylated liposomal doxorubicin as a synergistic ingredient: In vitro and in vivo evaluation in mice bearing C26 colon carcinoma and B16F0 melanoma. Eur J Pharm Sci.; 80: 66-73. doi: 10.1016/j.ejps.2015.08.011.

101) Nikpoor AR, Tavakkol-Afshari J, Gholizadeh Z, Sadri K, Babaei MH, Chamani J, Badiee A, Jalali SA, Jaafari MR. Nov. 10, 2015; Nanoliposome-mediated targeting of antibodies to tumors: IVIG antibodies as a model. Int J Pharm. 495(1):162-170. doi: 10.1016/j.ijpharm.2015.08.048.

102) Arabi L, Badiee A, Mosaffa F, Jaafari MR. 2015 Dec 28;  Targeting CD44 expressing cancer cells with anti-CD44 monoclonal antibody improves cellular uptake and antitumor efficacy of liposomal doxorubicin. J Control Release. 220(Pt A): 275-86. doi: 10.1016/j.jconrel.2015.10.044.

103) Amin M, Mansourian M, Koning GA, Badiee A, Jaafari MR, Ten Hagen TL. 2015 Dec 28;Development of a novel cyclic RGD peptide for multiple targeting approaches of liposomes to tumor region. J Control Release. 220(Pt A): 308-15. doi: 10.1016/j.jconrel.2015.10.039.

104)  Sadri K, Momenypoor S, Dabbagh Kakhki VR, Sadeghi R, Aryana K, Johari Daha F, Zakavi SR, Jaafari MR. 2015 Fall, Nano Liposomes Labeled with 99mTc-HMPAO, a Novel Agent for Blood Pool Imaging. Iran J Pharm Res.; 14 (4): 981-988.

105) Rahimi HR, Jaafari MR, Mohammadpour AH, Abnous K, Ghayour-Mobarhan M, Ramezanzadeh E, et al. 2015, Curcumin: Reintroduced Therapeutic Agent from Traditional Medicine for Alcoholic Liver Disease. Asia Pac J Med Toxicol. 4: 25-30.

106) Ghaffari-Nazari H, Tavakkol-Afshari J, Jaafari MR, Tahaghoghi-Hajghorbani S, Masoumi E, Jalali SA. 2015 Nov 10, Improving Multi-Epitope Long Peptide Vaccine Potency by Using a Strategy that Enhances CD4+ T Help in BALB/c Mice. PLoS One.; 2015 Nov 10;10(11):e0142563. doi: 10.1371/journal.pone.0142563. eCollection 2015.

107) Marzban E, Alavizadeh SH, Ghiadi M, Khoshangosht M, Khashayarmanesh Z, Abbasi A, Jaafari MR. 2015 Dec 1, Optimizing the therapeutic efficacy of cisplatin PEGylated liposomes via incorporation of different DPPG ratios: In vitro and in vivo studies. Colloids Surf B Biointerfaces.; 136: 885-891. doi: 10.1016/j.colsurfb.2015.10.046.

108) Alavizadeh SH, Akhtari J, Badiee A, Golmohammadzadeh S, Jaafari MR. 2016 Mar, Improved therapeutic activity of HER2 Affibody-targeted cisplatin liposomes in HER2-expressing breast tumor models. Expert Opin Drug Deliv. 13(3):325-36. doi: 10.1517/17425247.2016.1121987.

109) Mahboobeh NASSERI, Hossein AROUIEE, Shiva GOLMOHAMMADZADEH, Mahmoud Reza JAAFARI, Hossein NEAMATI, 2015, Antifungal Effects of Zataria multiflora Essential Oil on the Inhibitory Growth of some Postharvest Pathogenic Fungi, Not Sci Biol, 7(4): 412-416. DOI: 10.15835/nsb.7.4.9650.

110) Salarini R, Sahebkar A, Mirzaei HR, Jaafari MR, Riahi MM, Hadjati J, Asrami MO, Fdaee S, Salehi R, Mirzaei H., 2015 Dec 6., Epi-drugs and Epi-miRs: Moving beyond current cancer therapies. Curr Cancer Drug Targets. 2015 Dec 6. [Epub ahead of print].

111) Mirzaei H, Sahebkar A, Avan A, Jaafari MR, Salehi R, Salehi H, Baharvand H, Rezaei A, Hadjati J, Pawelek JM1, Mirzaei HR. Application of Mesenchymal Stem Cells in Melanoma: a potential therapeutic strategy for delivery of targeted agents. Curr Med Chem. 2015 Dec 17. [Epub ahead of print].

112) Mobasheri M, Attar H, Rezayat Sorkhabadi SM, Khamesipour A, Jaafari MR., 2015 Dec 24; Solubilization Behavior of Polyene Antibiotics in Nanomicellar System: Insights from Molecular Dynamics Simulation of the Amphotericin B and Nystatin Interactions with Polysorbate 80. Molecules. 21(1): 1-26. pii: E6. doi: 10.3390/molecules21010006.

113) Mehravaran A, Jaafari MR, Jalali SA, Khamesipour A, Tafaghodi M, Hojatizade M, Abbasi A, Badiee A. 2015 Dec; Cationic Immune Stimulating Complexes Containing Soluble Leishmania Antigens: Preparation, Characterization and in Vivo Immune Response Evaluation. Iran J Immunol. 12(4):274-87. doi: IJIv12i4A5.

114) YahyaHanafi-Bojd M, Jaafari MR, Ramezanian N, Abnous K, Malaekeh-Nikouei B. Co-delivery of Epirubicin and siRNA Using Functionalized Mesoporous Silica Nanoparticles Enhances In vitro and In vivo Drug Efficacy. Curr Drug Deliv. 2015 Dec 30. [Epub ahead of print].

115) Moosavian SA, Abnous K, Badiee A, Jaafari MR. 2016 Mar 1; Improvement in the drug delivery and anti-tumor efficacy of PEGylated liposomal doxorubicin by targeting RNA aptamers in mice bearing breast tumor model. Colloids Surf B Biointerfaces. 139: 228-236. doi: 10.1016/j.colsurfb.2015.12.009.

116) Mirzaei H, Sahebkar A, Jaafari MR, Hadjati J, Javanmard SH, Mirzaei HR, Salehi R. PiggyBac as a novel vector in cancer gene therapy: current perspective. Cancer Gene Ther. 2016 Jan 8. doi: 10.1038/cgt.2015.68. [Epub ahead of print].

117) Ahmad Mehravaran, Mahmoud Reza Jaafari, Seyed Amir Jalali, Ali Khamesipour, Reza Ranjbar , Mansure Hojatizade , Ali Badiee; Feb 2016 The role of ISCOMATRIX bilayer composition to induce a cell mediated immunity and protection against leishmaniasis in BALB/c mice. Iran J Basic Med Sci, 19 (2): 178-186.

118)  Mohammad Reza Ghazanfari, Mehrdad Kashefi, Mahmoud Reza Jaafari, (May 1, 2016), Modeling and optimization of effective parameters on the size of synthesized Fe3O4 superparamagnetic nanoparticles by coprecipitation technique using response surface methodology. Journal of Magnetism and Magnetic Materials, 405 : 88–96.

119) Zahmatkeshan M, Gheybi F, Rezayat SM, Jaafari MR. 2016 Apr 30, Improved drug delivery and therapeutic efficacy of PEGylated liposomal doxorubicin by targeting anti-HER2 peptide in murine breast tumor model. Eur J Pharm Sci. 86: 125-35. doi: 10.1016/j.ejps.2016.03.009.

120) Razavi-Azarkhiavi K, Jafarian AH, Abnous K, Razavi BM, Shirani K, Zeinali M, Jaafari MR, Karimi G. The Comparison of Biodistribution, Efficacy and Toxicity of Two PEGylated Liposomal Doxorubicin Formulations in Mice Bearing C-26 Colon Carcinoma: a Preclinical Study. Drug Res (Stuttg). 2016 Mar 29. [Epub ahead of print].

121) Akhtari J, Rezayat SM, Teymouri M, Alavizadeh SH, Gheybi F, Badiee A, Jaafari MR. 2016 May 1,Targeting, biodistributive and tumor growth inhibiting characterization of anti-HER2 affibody coupling to liposomal doxorubicin using BALB/c mice bearing TUBO tumors. Int J Pharm. 505: 89-95. doi: 10.1016/j.ijpharm.2016.03.060.

122) Fakhraee F, Badiee A, Alavizadeh SH, Jalali SA, Chavoshian O, Khamesipour A, Mahboudi F, Jaafari MR. May 2016, Coadminstration of L. major amastigote class I nuclease (rLmaCIN) with LPD nanoparticles delays the progression of skin lesion and the L .major dissemination to the spleen in BALB/c mice-based experimental setting. Acta Trop. 2016 Apr 6. 159: 211–218 doi: 10.1016/j.actatropica.2016.04.004.

                                                                      Presentations

1) Foldvari, M. and Jaafari, M.R. 1994. Effect of synthetic P0-oligopeptides on the cell adhesion properties of P0 protein reconstituted into liposomes. Pharmaceutical Research, 11(10) S-328 (Congress of American Association of Pharmaceutical Sciences, SanDiego, USA, November 6-10, 1994).

2) Jaafari, M.R. and Foldvari, M. 1997. Adhesive properties of P0 protein reconstituted into liposomes with different human melanoma cell lines. Pharmaceutical Research, 14(11) S-157 (Congress of American Association of Pharmaceutical Sciences, Boston, USA, November 2-6, 1997).

3) Jaafari, M.R. and Foldvari, M. 1997. Inhibition of adherence of jurkat T cells to keratinocytes by LFA-1 derived and RGD peptides. Pharmaceutical Research, 14(11) S-312 (Congress of American Association of Pharmaceutical Sciences, Boston, USA, November 2-6, 1997).

4) Jaafari, M.R. and Foldvari, M. 1998. Liposome targeting to melanoma cells through adhesive peptides from immunoglobulin (Ig) domains. Pharmaceutical Research, 15(11) Supplement (Congress of American Association of Pharmaceutical Sciences, San Francisco, USA, November 15-19, 1998).

5) Foldvari, M. and Jaafari, M.R. 1997. Studies of adhesive properties of myelin P0 protein derived peptides. In: Juurlink, B.H.J., Devon, R.M., Doucette, J.R., Nazarali, A.J  Cell Biology and Pathology of Myelin : Evolving Biological Concepts and Therapeutic Approaches (Altschul Symposia Series: Cell Biology and Pathology of Myelin : Evolving Biological Concepts and Therapeutic Approaches, Saskatoon, Canada June 27-29, 1996).

6) Jaafari M.R., Khamesipour A., Hemedivafa F., koushkbaghy M. 2001, Inducing cell- mediated immunity in BALB/C mice using liposomes encapsulated with crude Leishmania antigens (CLA) (WORLDleish 2, MAY 20-24, 2001, Crete, Greece).

7) Jaafari M.R., Sadri K., Arefee A., Amani M., Mahboudi  F. Protection of BALB/c mice against cutaneous leishmaniasis by immunization with recombinant leishmania major surface glycoprotein (rGP63)/ liposomes  (Pharmacy and Pharmaceutical Sciences World Congress, Nice, France, Sept. 2002).

8) M. Tabbakhian, S. Daneshamouz, M. R. Jaafari, N. Tavakoli,  Preparation and Characterization of niosomes containing finasteride  (AAPS American Association of pharmaceutical Sciences annual meeting and expositon Toronto, Canada  Nov. 10-15, 2003).

9) M. R. Jaafari, A. Arefee, K. Sadri, M. Amani and F. Mohboudi, Vaccination of BALB/c mice against cutaneous leishmaniasis using fusogenic liposomes incorporated with recombinant major surface glycoprotein of leishmania (rGP63), Journal of Pharmacy and Pharmacology, 55: S-69 (2003), (British Pharmaceutical Conference, Harrogate, UK, Sept. 15-17, 2003).

10) M. R. Jaafari, A. Ghafarian, A. Farrokh-Gisour, M. Amani and F. Mahboudi, 2003,Vaccination of BALB/c mice against cutaneous leishmaniasis using neutral liposomes incorporated with recombinant major surface glycoprotein of  of leishmania (rGP63). Sixth Int. Conference, Liposome Advances: Progress in drug and vaccine delivery, School of Pharmacy, University of London, Dec. 15-19, 2003, London, UK, Abstract book: page 97.

11) Y. Sohrabi, M. R. Jaafari, A., A. Miramin Mohammadi and A. Khamesipour, Induction of cell mediated immunity  against leishmaniasis using mannan coated liposomes containing autoclaved leishmania major. Sixth Int. Conference, Liposome Advances: Progress in drug and vaccine delivery, School of Pharmacy, University of London, Dec. 15-19, 2003, London, UK, Abstract book: page 128.

12) A. Khamesipour, M. R. Jaafari, A., A. Miramin Mohammadi and Y. Sohrabi, 2003,Vaccination of BALB/c mice  with liposomes/autoclaved leishmania major composed of different phospholipids. Sixth Int. Conference, Liposome Advances: Progress in drug and vaccine delivery, School of Pharmacy, University of London, Dec. 15-19, 2003, London, UK, Abstract book:  page 108.

13) M. R. Jaafari, A. Ghafarian, A. Farrokh-Gisour, M. Amani and F. Mahboudi, Vaccination of BALB/c mice against cutaneous leishmaniasis using mannan coated positively charged liposomes incorporated with recombinant major surface glycoprotein of leishmania (rGP63). 9th Liposome Research Days, Above and Beyond, May 11-15, 2004, Hsinchu, Taiwan, Abstract book:  page 110.

14) Tafaghodi M., Sajadi S.A., Jaafari M.R., Zakavi S.R., Momen-Nejad M.  Gamma-scintigraphic evaluation of the clearance characteristics of microspheres in the human nose, 2nd Pharmaceutical Sciences World Congress, The Global Translational of science into Drug Development in Advancing Therapy, May 30-June 3, 2004, Kyoto, Japan, Abstract book: page 253.

15) Sajadi Tabassi S.A., Tafaghodi M., Jaafari M.R., Dextran microspheres as a potential delivery systems for nasa immunization- in vitro and in vivo characterization, Proc. International Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Nuremberg, 15-18 March 2004., page 501-502.

16) Jaafari, M.R. Badiee A. Samiei A., Soroush D., Khamesipour A., Amani M., Mahboudi F., Vaccination of BALB/c Mice against cutaneous leishmaniais (CL) using lipsomes containing recombinant major surface glycoprotein of leishmania (rGP63) and CPG ODNs, WORLDleish 3, April 10-15, 2005, Terrasini, Palermo, Italy Abstract book: page: 257.

 

17) Sohrabi Y., Jaafari M.R., Miramin Mohammadi A.,  Eskandari S.E., Khamesipour A., Evaluation of immune response against leishmaniasis induced by liposomes containing freeze/thawed thimrosal treated L. major (KLM) in C57BL/6 MICE, WORLDleish 3, April 10-15, 2005, Terrasini, Palermo, Italy Abstract book: page: 279.

18) Badiee A., Jaafari M.R., Samiei A., Soroush D., Webb J., Khamesipour A., Immunization of BALB/c mice against cutaneous leishmaniasis (CL) using lipsomes containing rLmSTI1 and CPG ODNs, WORLDleish 3, April 10-15, 2005, Terrasini, Palermo, Italy Abstract book: page: 238.

 

19) Sohrabi Y., Jaafari M.R., Miramin Mohammadi A.,  Eskandari S.E., Khamesipour A., 2005, Evaluation of immune response against leishmaniasis in resistance C57BL/6 mice immunized with liposomes containing autoclaved leishmania major with BCG. Cell. Mol. Biol. Lett., 10 (Supp.): 98.

20) Ramezani M., Emamy J.A., Jaafari M.R., Behravan M., Evaluation of leishmaniacidal effect of Euphorbia bunjei extract by in vitro leishmaniacidal assay using promastigotes of L. major, AHAT BSAS International Conference, Nov. 14-18, 2005, Khon Kaen, Thailand, P20-21.

21) Sajadi Tabassi S.A., Tafaghodi M., Jaafari M.R. Nasal immunization studies by cationic, fusogenic and cationic-fusogenic liposomes encapsulated with tetanus toxoid, 9th Commonwealth Pharmaceutical Association Conference, 1-5 August 2007, Kuala Lumpur, Malaysia, Abstract book, P 116.

22) Mahmoud R Jaafari, Zhaohua Huang, Francis C Szoka, New lipids for liposome construction and use in the treatment of cancer. International Liposome Society 2007 Annual Meeting, Liposome Advances: Progress in Drug and Vaccine Delivery, School of Pharmacy, University of London, Dec. 8-11, 2007, London, UK, Abstract book:  page 28 (Podium Presentation)

23) M. R. Jaafari, A. Badiee, A. Khamesipour, A. Samiei, M. Tavassoti Kheiri, F. Barkhordari, and F. Mohboudi, Enhancement of immune response and protection in BALB/c mice immunized with liposomal recombinant major surface glycoprotein of leishmania (rGP63): The role of bilayer composition, International Liposome Society 2007 Annual Meeting, Liposome Advances: Progress in Drug and Vaccine Delivery, School of Pharmacy, University of London, Dec. 8-11, 2007, London, UK, Abstract book:  page 65 (Poster Presentation).

24) Zhaohua Huang, Mahmoud R Jaafari, Francis C Szoka, Evaluation of nanolipid formulations as drug carriers, 9th US-Japan Symposium on Drug Delivery Systems, The Westin  Maui, Lahaina, Maui, Hawaii, December 16-20, 2007.

25) M. R. Jaafari, A. Khamesipour, A. Samiei, D. Soroush, M. Tavassoti Kheiri, F. Barkhordari, and F. Mohboudi, Vaccination of BALB/c mice against cutaneous leishmaniasis using LPD nanoparticles containing rLmaCIN prepared with CpG Oligodeoxynucleotides. 11th Liposome Research Days Conferences, Innovation from Liposome, July 19-22, 2008, Yokohama, Japan, Abstract Book:  page 211.

26) M. R. Jaafari, A. Badiee, A. Khamesipour, A. Samiei, D. Soroush, M. Tavassoti Kheiri, F. Barkhordari, and F. Mohboudi, The role of liposome charge on immune response generated in BALB/c mice immunized with recombinant major surface glycoprotein of leishmania (rGP63). 11th Liposome Research Days Conferences, Innovation from Liposome, July 19-22, 2008, Yokohama, Japan, Abstract Book:  page 216.

27) N. Bavarsad, M. R. Jaafari, S. Fazly Bazaz, M. M. Lotfi Heravi, S. Ghorbani, A. Samiei, D. Soroush, A. Khamesipour, Activity of topical liposomes containing paromomycin sulfate against experimental cutaneous leishmaniasis. 11th Liposome Research Days Conferences, Innovation from Liposome, July 19-22, 2008, Yokohama, Japan, Abstract Book:  page 122.

28) B. Malaekeh-Nikouei, M. R. Jaafari, S. A. Sajadi Tabassi, A. Samiei, The effect of phospholipid type and size on immunosuppressive activities of liposomes encapsulated with Cyclosporine A. 11th Liposome Research Days Conferences, Innovation from Liposome, July 19-22, 2008, Yokohama, Japan, Abstract Book:  page 208.

29) Maryam Iman, Zhaohua Huang, Francis C. Szoka, Jr.and Mahmoud R. Jaafari Colloidal, relative toxicity and in vivo antileishmanial properties of liposome-intercalated Amphotericin B prepared from distigmasterylhemisuccinoyl-glycero-phosphocholin, International Liposome Research Days and Lipids, Liposomes and Membrane Biophysics, Aug. 4-8, 2010,  University of British Colombia, Vancouver, Canada.

30) Mohamadreza Amin, Ali Badiee, Mahmoud Reza Jaafari, Biodistribution of RGD-targeted liposomes containing doxorubicin in mice bearing C-26 colon Carcinoma, ESF-UB Conference in Biomedicine on Nanomedicine: Reality Now and Soon, 23-28 October 2010 Sant Feliu, Spain.

31) Mahmoud R. Jaafari, Zhaohua Huang  & Francis C. Szoka, Sterol Modified Lipids for Improved Liposome Anticancer Drug Formulation, 3rd Conference on Nanostructures, March 10-12, 2010, Sharif University of Technology, International Campus, Kish Island, Iran.

32) F. Hoda Alavizadeh, Mahmoud R. Jaafari, Ali Badiee, Ali Khamesipour, Amir Jalali, Azam Abbasi, Evaluation of lesion development and type of immune response generated in mice inoculated with L.major mixed with LPD nanoparticles containing CpG ODN, 3rd Conference on Nanostructures, March 10-12, 2010, Sharif University of Technology, International Campus, Kish Island, Iran.

33) Maryam Iman, Zhaohua Huang, Francis C. Szoka, Jr.and Mahmoud R. Jaafari, Nanoliposomes prepared from distigmasterylhemisuccinoyl-glycero-phosphocholin: Novel Amphotericin B nano-carrier with low toxicity, 12th Iranian Pharmaceutical Sciences Congress, Aug. 2-5, 2010, Zanjan, Iran.

34) Mohamadreza Amin, Ali Badiee, Mahmoud Reza Jaafari, Biodistribution of RGD-targeted liposomes containing doxorubicin in mice bearing C-26 colon Carcinoma, ESF-UB Conference in Biomedicine on Nanomedicine: Reality Now and Soon, 23-28 October 2010, Hotel Eden Roc, Sant Feliu de Guixols, Spain.

35) Mohamadreza Amin, Ali Badiee, Mahmoud Reza Jaafari, Antitumor efficacy of RGD-targeted liposomes containing doxorubicin in mice bearing C-26 colon Carcinoma. International Liposome Society 2011 Annual Meeting, Liposome Advances: Progress in Drug and Vaccine Delivery, School of Pharmacy, University of London, Dec. 10-13, 2011, London, UK, Abstract book:  page 63 (Poster Presentation).

                                                                    Honors & Awards

Scholarship award for higher education by the Ministry of Health and Medical Education of Iran, 1993-1996.

The Parke-Davis Centennial Pharmacy Research Award, 1996-1997 and 1997-1998.

The 13th Razi Research Festival on Medical Sciences, Second Rank in Modern Technology (Nanotechnology and Biotechnology), www.razi.hbi.ir, December 2007.

Members                                                  hip Membership

Editorial Board of:

            Directing Manager of Nanomedicine Journal

American Journal of Current Immunology

            ISRN Pharmaceutics

            BioImpact

SM Journal of Nanotechnology and Nanomedicine

                                                           Administrative Responsibilities

Founder of Exir Nano Sina Company:

Exir Nano Sina Company (ENSC, http://exirnanosina.ir) founded by Prof. Mahmoud R. Jaafari from School of Pharmacy, Mashhad University of Medical Sciences with the support of Iranian Nanotechnology Initiative Council in 2009. ENSC is a knowledge-based nanopharmaceutical company focused on the research, development and commercialization of innovative nanopharmaceutical products based on its proprietary drug delivery technologies. Our strengths lie in lipid-based formulation and scale-up for parenteral, oral and topical drugs using liposomes, micelles and nanoparticles to optimize the pharmacokinetics of drugs for better efficacy and lower toxicity, and thus prolong the product lifecycle of branded drugs.

ENSC produce PEGylated liposomal doxorubicin with the trade name of SinaDoxosome® for the treatment of cancer, Curcumin nanomicelles (SinaCurcumin®) as supplement and topical nanoliposomal Amphotericin B (SinaAmpholeish®) for the treatment of cutaneous leishmaniasis.

 

Patents:

1)      United States Patent Application Publication: 2015   Mahmoud Reza Jaafari, Ali Khamesipour,  TOPICAL LIPOSOMAL COMPOSITIONS FOR DELIVERING HYDROPHOBIC DRUGS AND METHODS PREPARING SAME, Publication Number: US 2015/0147382 A1.

2)      United States Patent Application Publication 2015  Amirhossein Sahebkar, Ali Badiee, Mahmoud Reza Jaafari,  METHOD AND COMPOSITION FOR TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES, Publication Number: US 2015/0147383 A1.

3)      United States Patent Application Publication: 2016   Mahmoud Reza Jaafari, Seyed Mahdi Rezayat, Javad Akhtari, TARGETING LIPOSOMAL COMPOSITION USING ANTI-HER2 AFFIBODY MOLECULES AND APPLICATIONS THEREOF IN CANCER TREATMENT, Publication Number: US 2016/0045614 A1.

4)      2015   Mahmoud Reza Jaafari, Seyed Mahdi Rezayat, Fatemeh Ghaibi, LONG CIRCULATING LIPOSOMES CONTAINING SILYBIN AND SILYMARIN AND USE THEREOF IN CANCER TREATMENT, Provisional Patent Application Number in USPTO: US 62245988.

5)      2015   Mahmoud Reza Jaafari, Seyed Mahdi Rezayat, Fatemeh Ghaibi, POLY ETHYLENE GLYCOL-PHOSPHOLIPID CONJUGATED MOLECULES WITH CYTOTOXIC EFFECTS, SYNTHESIZING THE SAME AND USE THEREOF IN CANCER TREATMENT, Provisional Patent Application Number in USPTO: US 62173941.

6)      2015   Mahmoud Reza Jaafari, Masoumeh Zahmatkeshan, Seyed Mahdi Rezayat, CANCER-TARGETED PEPTIDES AND APPLICATIONS THEREOF, Provisional Patent Application Number in USPTO: US 62217877.

7)      2015   Mahmoud Reza Jaafari, Shahrzad Amiridarban, Ali Badiee, TARGETING HDM2 EXPRESSING CANCER CELLS WITH A NOVEL PEPTIDE AND APPLICATIONS THEREOF IN CANCER TREATMENT, Provisional Patent Application Number in USPTO: US 62272701.

Professional Experience:

1988-1993:      Instructor of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

 

1999-2004:      Assistant Professor of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran                                          

 

2004-2009:       Associate Professor of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

2009-:              Professor of Pharmaceutics and Pharmaceutical Nanotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

 

2003-2004:      Dean of Pharmaceutical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

2004-2006:      Dean of Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

2008-2010:      Director of Nanotechnology Council, Mashhad University of Medical Sciences, Mashhad, Iran

2010-:              Dean of Nanotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

2011-:              Head of Pharmaceutical Nanotechnology Department, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

2014-:              Head of Committee of Technologies and Innovations in Medical Researches, National Institute for Medical Research Development (NIMAD)

 

Other Skills

Teaching Responsibilities:

Various topics in pharmaceutics and Pharmaceutical Nanotechnology: Targeted drug delivery, Liposomal drug delivery, Gene Delivery, Nanopharmaceutics, NanoBiotechnology, and  Peptide and protein formulation and delivery

 

 

امتیاز کاربران

ستاره غیر فعالستاره غیر فعالستاره غیر فعالستاره غیر فعالستاره غیر فعال

Curriculum Vitae   

 

Bizhan Malaekeh-Nikouei (Pharm.D, Ph.D.)

 

Professor in Pharmaceutics,

School of Pharmacy and Nanotechnology Research Center,

Mashhad University of Medical Sciences (MUMS),

Mashhad, Iran

P.O. Box: 91775-1365

Phone: +98 51 38823255-6

E-mail: این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید

 

Gender: male

Date of birth: June 24th, 1976

Place of birth: Mashhad, Iran

Residence: Mashhad, Iran

Marital status: Married

Number of Children: 2

 

 

Education:

- Sabbatical (6 months) in University of Utah, USA (2013)

-  Research fellowship (6 months) in University of Queensland, Australia (2005)

- Ph.D. in Pharmaceutics from School of Pharmacy, Mashhad University of Medical Sciences (2001-2006)                                    

- Pharm.D. from School of Pharmacy, Tabriz University of Medical Sciences (1994 -1999)

 

 

Research interests:

Particulate drug delivery systems including Microspheres and Nanospheres, Liposomes, Solid lipid nanoparticles (lipospheres), Nanobiotechnology, Designing of non-viral vectors, Targeted drug delivery

 

Editorial Board Member:

-         Iranian Journal of Basic Medical Sciences

-         Nanomedicine Journal

-         International Journal of Ophthalmic Research

 

Publications:

1)    Hasanzadeh D., Malaekeh-Nikouei B., 1997, Quantitative analysis of H2-blockers by FT-IR: comparison with HPLC method, Pharmaceutical Sciences (Journal of Tabriz Faculty of Pharmacy), 3, 25-32. (Persian)

2)    Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., 2004, Preparation and characterization of biodegradable microspheres encapsulated with cyclosporine A using different grades of  PLGA, Iranian Journal of Basic Medical Sciences, 7, 4, 240-249 (Persian).

3)    Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., Samiee A., 2005, Preparation of fusogenic liposomes encapsulated with cyclosporine A and evaluation of its immunosuppressive effects on human T-cells, Pharmaceutical Sciences (Journal of Tabriz Faculty of Pharmacy), 2, 1-9 (Persian).

4)    Jaafari M. R., Malaekeh-Nikouei B., Nasirli H., Hosseinzadeh H., 2005, Formulation of topical liposomes encapsulated with triamcinolone and comparison of their anti-inflammatory effects with available conventional topical ointment in mice, Iranian Journal of Basic Medical Sciences, 8, 3, 195-201 (English).

5)    Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., Davies N. M., 2005, Preparation and characterization of PLGA microspheres loaded by cyclosporine-cyclodextrin complex, Iranian Journal of Pharmaceutical Sciences, 1, 4, 195-201 (English).

6)    Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., 2006, The effect of different grades of PLGA on characteristics of microspheres encapsulated with cyclosporine A, Current Drug Delivery, 3, 4, 343-349 (English).

7)    Malaekeh-Nikouei B., 2006, Liposomes as novel drug delivery system, Razi, 211, 59-64 (Persian).

8)    Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., Davies N. M., 2006, The effect of complexation on characteristics and drug release of PLGA microspheres loaded by cyclosporine-cyclodextrin complex, Journal of Drug Delivery Science and Technology, 16(5), 345-350 (English).

9)    Malaekeh-Nikouei B., Nassirli H., Davies N. M., 2007, Enhancement of cyclosporine aqueous solubility using α- and hydroxypropyl β-cyclodextrin mixtures, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 59 (3-4), 245-250 (English).

10)         Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., 2007, Preparation, characterization and mucoadhesive evaluation of chitosan coated liposomes containing cyclosporine A, Saudi Pharmaceutical Journal, 15, 3-4, 176-182 (English).

11)         Malaekeh-Nikouei B., Abrishami M., Zarei S., 2008, Liposomal formulation of bevasizuamb for intravitreal administration: increased half-life, decreased side effects, Iranian Journal of Medical Hypotheses and Ideas, 2:4, (Persian).

12)         Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., 2008, Preparation, characterization and mucoadhesive properties of chitosan coated microspheres encapsulated with cyclosporine A, Drug Development and Industrial Pharmacy, 34, 5, 492-498 (English).

13)         Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., Samiee A., 2008, The Enhancement of Immunosuppressive Effects of Cyclosporine A on Human T-Cells Using Fusogenic Liposomes, Colloids and Surfaces B:Biointerfaces, 67, 238-244 (English).

14)         Abrishami M., Zarei-Ghanavati S., Soroush D., Rouhbakhsh M., Jaafari M. R., Malaekeh-Nikouei B., 2009, Preparation, characterization and in vivo evaluation of nanoliposomes encapsulated bevacizuamb for Intravitreal administration, Retina, 29, 5, 699-703 (English).

15)         Malaekeh-Nikouei B., Davies N. M., 2009, Double loading of cyclosporine A in liposomes using cyclodextrin complexes, PDA Journal of Pharmaceutical Science and Technology, March-April,  63(2), 139-148 (English).

16)         Ramezani M., Khoshhamdam M., Dehshahri A., Malaekeh-Nikouei B., 2009, The influence of size, lipid composition and bilayer Tm on the transfection efficiency of nanolipoplexes, Colloids and Surfaces B:Biointerfaces, 72(1), 1-5 (English).

17)         Malaekeh-Nikouei B., Malaekeh-NikoueiM., Kazemi OskueeR., RamezaniM., 2009, Preparation, characterization and transfection efficiency of nanoliposomes modified with oligoamines as gene carrier, Nanomedicine: Nanotechnology, Biology, and Medicine, 5, 457–462 (English).

18)         Malaekeh-Nikouei B., Sajadi Tabassi S.A., Ashari H., Gholamzadeh A., 2009, Evaluation the effect of cyclodextrin complexation on aqueous solubility of fluorometholone to achieve ophthalmic solution, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 65, 335-340 (English).

19)         Ramezani M., Khakshoor T., Malaekeh-Nikouei M., Malaekeh-Nikouei B., 2010, The effect of linear PEI on characteristics and transfection efficiency of PEI-based cationic nanoliposomes, Iranian Journal of Basic Medical Sciences, 4,1, 82-88 (English).

20)         Motaharinia J., Ramezani M., Malaekeh-Nikouei M., Malaekeh-Nikouei B., 2011, Liposome-linear polyethyleneimine-DNA Nanocomplexes for Gene Delivery: Preparation, Characterization and In Vitro Transfection Activity, Current Nanoscience, 7, 587-593 (English).

21)         Mousavi S.H., Moallem S.A., Mehri S., Shahsavand S., Nassirli H., Malaekeh-Nikouei B., 2011, Improvement of cytotoxic and apoptogenic properties of crocin in cancer cell lines by its nanoliposomal form, Pharmaceutical Biology, 49(10), 1039–1045, (English).

22)         Malaekeh-Nikouei B., Banaee T., Aghamohammadian J., Mosallaei N., Mohajeri SA., 2011, Quantitative LC Analysis of Cyclosporine A in Ocular Samples, Chromatographia, 73:817–821, (English).

23)         Malaekeh-Nikouei B., Golmohammadzadeh S., Hosseini M., Nassirli H., 2011, Preparation and characterization of liposomes encapsulated with clindamycin and tretinoin, Pharmacie Globale (IJCP), 6 (03), (English).  

24)         Asili J., Mosallaei N., Shaterzadeh A., Malaekeh-Nikouei B.,  2012, Preparation and characterization of liposomes containing methanolic extract of aerial parts of Platycladus orientalis (L.) Franco, Avicenna Journal of Phytomedicine, 2, 1, 17-23 (English).

25)         Ramezani M., Malaekeh-Nikouei B.,Motaharinia J., Malaekeh-Nikouei M., 2011, Glactosylated liposome-polyethyleneimine-DNA nanocomplexes as a non-viral vector, Pharmacie Globale (IJCP), 10 (03) (English).

26)         Tavallaie S., Zobeiri M., Haghighat-Khazaee Z., Hassanzadeh-Khayyat M., Nassirli H., Malaekeh-Nikouei B., Sahebkar A., Ghayour-Mobarhan M., 2012, Serum vitamin E concentration in Iranian population with angiography defined coronary artery disease, Asian Biomedicine, 6, 1, 19-25 (English).

27)         Mohajeri SA, Malaekeh-Nikouei B., Sadegh H., 2012, Development of a pH-responsive drug delivery system for diclofenac using molecularly imprinted polymers, Drug Development and Industrial Pharmacy, 38(5):616-22 (English).

28)         Malaekeh-Nikouei B., Sajadi Tabassi S.A., Gerayeli G., Arab Salmani M., Gholamzadeh A., 2012, The effect cyclodextrin mixtures on the aqueous solubility of beclomethasone dipropionate, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 72, 383-387 (English).

29)         Rafiee E., Eavani S., Malaekeh-Nikouei B., 2012, 12-Tungstophosphoric Acid Immobilized on γ-Fe2O3@SiO2 Core–Shell Nanoparticles: An Effective Solid Acid Catalyst for the Synthesis of Indole Derivatives in Water, Chemistry Letters, 41, 4, 438-440 (English).

30)         Malaekeh-Nikouei B., Abbasi Ghaeni F., MotamedshariatyV., Mohajeri SA, 2012, Controlled release of prednisolone acetate from molecularly imprinted hydrogel contact lenses, Journal of Applied Polymer Science, 126, 1, 387-394 (English).

31)         Mosallaei N., Banaee T., Farzadnia M., Abedini E, Ashraf H, Malaekeh-Nikouei B., 2012, Safety evaluation of nanoliposomes containing cyclosporine A after ocular administration, Current Eye Research, 37, 6, 453-456 (English).

32)         Ramezani M., Malaekeh-Nikouei B.,Malekzadeh S., Baghayeripour M.R., Malaekeh-Nikouei M., 2012, The effect of lipopolymer structure on the transfection efficiency of hydrophobic PEI-based cationic nanoliposomes, Current Nanoscience, 8, 5, 680-684 (English).

33)         Zarei-Ghanavati S., Malaekeh-Nikouei B., Pourmazar R., SeyediS., 2012, Preparation, characterization and in vivo evaluation of microspherical triamcinolone acetonide after intravitreal administration, Journal of Ocular Pharmacology and Therapeutics, 28 (5), 502-506  (English).

34)         Malaekeh-Nikouei B., Fazly Bazzaz B.S., Soheili V., Mohammadian K., 2013, Problems in ophthalmic drug delivery: evaluation of interaction between preservatives and cyclodextrins, Jundishapur Journal of Microbiology, 6(5), e6333 (English).

35)         Hosseinzadeh H., RamezaniM., Tavakoli AnarakiN., Malaekeh-NikoueiB., MohammadpourA.H., 2013, Development and validation of extraction and HPLC method for determination of crocetin in human serum samples, Iranian Journal of Basic Medical Sciences, 15, 1, 47-55 (English).

36)         Malaekeh-Nikouei B., Mousavi SH, Shahsavand S, Mehri S, Nassirli H, Moallem SA., 2013, Assessment of cytotoxic and apoptogenic properties of safranal and nanoliposomal safranal in various cancer cell lines, Phytotherapy Research, 27, 1868-1873 (English).

37)         Malaekeh-Nikouei B., Golmohammadzadeh S., Salmani-Chamanabad S., Mosallaei N., Jamialahmadi K., 2013, Preparation, characterization and moisturizing effect of liposomes containing glucosamine and N-acetyl glucosamine, Journal of Cosmetic Dermatology, 12, 96-102 (English).

38)         Malaekeh-Nikouei B., Vahabzadeh S.A., Mohajeri S.A., 2013, Preparation of a molecularly imprinted soft contact lens as a new ocular drug delivery system for dorzolamide, Current Drug Delivery, 2, 3, 279 -285 (English).

39)         MosallaeiN., JaafariM.R., Hanafi-BojdM.Y., GolmohammadzadehS., Malaekeh-NikoueiB., 2013, Docetaxel loaded solid lipid nanoparticles: Preparation, characterization, in-vitro and in-vivo evaluations, Journal of Pharmaceutical Sciences, 102, 6, 1994-2004 (English).

40)         Iranshahi M., Esfahanizadeh T., Jalili-Jamshidian E., Hanafi-Bojd M.Y., Malaekeh-Nikouei B., 2013, Improvement the aqueous solubility of the prenylated coumarins using cyclodextrin complexation, International Journal of Pharmaceutical Research, 5, 3, 40-42 (English).

41)         Eslampour A., Malaekeh-Nikouei B.,  Abrishami M., Bayani R., 2013, Efficacy of extended-release oral diclofenac in postoperative pain management after photorefractive keratectomy, Journal of Ocular Pharmacology and Therapeutics, 29(7), 670-673 (English).

42)         Nikofal S., Mohajeri S.A., BanaeeT., Malaekeh-Nikouei B., 2013, Evaluation of cyclosporine A eye penetration after administration of liposomal or conventional forms in animal model, Nanomedicine Journal, 1, 1, 52-58 (English).

43)         Oskuee R.K., Mohtashami E., Golami L., Malaekeh-Nikouei B., 2014, Cationic Liposomes-Polyallylamine-Plasmid Nanocomplexes for Gene Delivery, Journal of Experimental Nanoscience, 9, 10, 1026-1034 (English).

44)         Malaekeh-NikoueiB., 2014, A brief report on Iranian Journal of Basic Medical Sciences in 2013, Iranian Journal of Basic Medical Sciences, 17, 3, 149 (Editorial) (English).

45)  Fazly Bazzaz B.S., Khameneh B., Jalili-Behabadi M., Malaekeh-Nikouei B.,  Mohajeri S.A., 2014, Preparation, characterization and antimicrobial study of a hydrogel (soft contact lens) material impregnated with silver nanoparticles, Contact Lens & Anterior Eye, 37, 149-152 (English).

46)  Ramezani A., Mehrdad Iranshahi M., Hanafi-Bojd, M.H., Malaekeh-Nikouei B., 2014, Preparation, characterization and cytotoxic effects of nanoliposomes containing umbelliprenin, International Journal of Pharmaceutical Research, 6, 2, 79-86 (English).

47)  Mahmoudi A., Oskuee R.K., Ramezani M., Malaekeh-Nikouei B., 2014, Preparation and in-vitro transfection efficiency evaluation of modified cationic liposome-polyethyleneimine-plasmid nanocomplexes as a novel gene carrier, Current Drug Delivery, 11, 5, 636-642 (English).

48)         Moghadas Sharif N., Fazly BazzazB.S., Khameneh BagheriB., Malaekeh-Nikouei B., 2015, The effect of nanoliposomes containing vancomycin and rifampin on Staphylococcus epidermidis biofilm, Drug Development and Industrial Pharmacy, 41, 3, 445-450 (English).

49)  Oskuee R.K., Dosti F., Gholami L., Malaekeh-Nikouei B., 2015, A simple approach for producing highly efficient DNA carriers with reduced toxicity based on modified polyallylamine, Materials Science and Engineering C, 49, 290-296  (English).

50)  Hanafi-BojdM.Y., Jaafari M.R., Ramezanian Xue M., AminM., ShahtahmasbiN., Malaekeh-Nikouei B., 2015, Surface Functionalized Mesoporous Silica Nanoparticles as an effective carrier for Epirubicin delivery to cancer cells, European Journal of Pharmaceutics and Biopharmaceutics, 89, 248-258 (English).

51)  Oskuee R.K., Zakeri V., Gholami L., Malaekeh-Nikouei B., 2015, Preparation, characterization and transfection efficiency of nanoparticles composed of bromoalkane modified polyallylamine, Nanomedicine Journal, 2, 2, 111-120 (English).

52)         Malaekeh-NikoueiB., Roohbakhsh A., 2015, Iranian Journal of Basic Medical Sciences: 2014 in profile, Iranian Journal of Basic Medical Sciences, 18, 1, 1 (Editorial) (English).

53)         Gholamzadeh A., Amini S., Mohammadpour A.H., Vahabzadeh M., Fazelifar A.F., Fazlinezhad A., Dehghani M., Moohebati M., Dastani M., Malaekeh-Nikouie B., Falsoleiman H., 2015, Erythropoietin reduces post-PCI arrhythmias in patients with ST-elevation myocardial infarction, Journal of Cardiovascular Pharmacology, 65(6):555-61 (English).

54)         Sadeghnia H., Zoljalali N., Hanafi-Bojd M.Y., Nikoofal-Sahlabadi S., Malaekeh-Nikouei B., 2015, Effect of mesoporous silica nanoparticles on cell viability and markers of oxidative stress, Toxicology Mechanisms and Methods, 25, 6, 433-439 (English).

55)         Naji-Tabasi S., Razavi S.M.A., Mohebbi  M., Malaekeh-Nikouei B., 2016, New studies on basil (Ocimum bacilicum L.) seed gum: Part I- Fractionation, physicochemical and surface activity characterization, Food Hydrocolloids, 52, 350-358 (English).

56)         Mahyari S., Mahyari B., Emami S.A., Malaekeh-Nikouei B., Jahanbakhsh S.P., Mohammadpour A.H., Sahebkar A., 2016, Evaluation of the efficacy of a polyherbal mouthwash containing Zingiber officinale, Rosmarinus officinalis and Calendula officinalis extracts in patients with gingivitis: A randomized double-blind placebo-controlled trial. Complementary Therapies in Clinical Practice 22, 93-98 (English).

57)         Roohbakhsh A., Malaekeh-NikoueiB., 2016, Iranian Journal of Basic Medical Sciences 2015 at a glance, Iranian Journal of Basic Medical Sciences, 19, 1, 1 (Editorial) (English).

58)         Mosallaei N., Mahmoudi A., Ghandehari H., Venkata Kashyap Yellepeddi V.K., Jaafari M.R., Malaekeh-Nikouei B., 2016, Solid Lipid Nanoparticles containing 7-ethyl-10-hydroxycamptothecin (SN38): Preparation, characterization, in vitro, and in vivo evaluations, European Journal of Pharmaceutics and Biopharmaceutics, 140, 42-50 (English).

59)         Oskuee R.K., Mahmoudi A., Gholami L., Rahmatkhah A., Malaekeh-Nikouei B., 2016, Cationic liposomes modified with polyallylamine as a gene carrier: Preparation, characterization and transfection efficiency evaluation, Advanced Pharmaceutical Bulletin, (Accepted) (English).

60)         Oskuee R.K., Ramezanpoor M., Gholami L., Malaekeh-Nikouei B., 2016, Cholesterol improves the transfection efficiency of polyallylamine as a non-viral gene delivery vectors, Advanced Pharmaceutical Bulletin (Accepted) (English).

61)         Rezaee M., Kazemi Oskuee R., NassirliH., Malaekeh-NikoueiB., 2016, Progress in the development of lipopolyplexes as efficient non-viral gene delivery systems, Journal of Controlled Release, 236, 1-14 (English) (Review).

62)         Hanafi-BojdM.Y., Jaafari M.R., Ramezanian Xue M., AminM., ShahtahmasbiN., Malaekeh-Nikouei B., 2016, Co-delivery of epirubicin and siRNA using functionalized mesoporous silica nanoparticles enhances in vitro and in vivo drug efficacy, Current Drug Delivery, (Accepted) (English).

 

             

Presentations:

1)    Malaekeh-Nikouei B., Nanomedicine, The 6th Annual Meeting of The Iranian Research Association for Vision and Ophthalmology, March 3-4, 2016, Tehran, Iran (Invited Speaker).

2)    Malaekeh-Nikouei B., AbrishamiM., AbrishamiM., MahmoudiA., MosallaeiN., Vikili Ahrari Roodi M., Preparation, Characterization, and In Vivo Evaluation of Solid Lipid Nanoparticles Containing Diclofenac after Intravitreal Administration, 1st International Gazi Pharma Symposium, November 12–15, 2015, Antalya, Turkey.

3)    Malaekeh Nikouei B., Oskuee R.K., Doosti F., Preparation, characterization and transfection efficiency of nanoparticles composed of modified polyallylamine, Miptec2014, 23-25 September 2014, Basel, Switzerland.

4)     Malaekeh-Nikouei B.,Banaee T.,Mosallaei N., Farzadnia M., Abedini E., Ashraf H., Preparation, characterization and safety evaluation of nanoliposomal formulations containing cyclosporine A, NanoFormulation, 28 May-1June 2012, Spain.

5)    Malaekeh-Nikouei B.,Ramezani M., Arabi L., Transfection efficiency of hydrophobic polyethyleneimine-based cationic nanoliposomes, Nanoscience and Nanotechnology Conference, September 19-23, 2011, Italy.

6)    Malaekeh-Nikouei B., Zarei-Ghanavati S., Pourmazar R., Seyedi S., Microspheres containing triamcinolone acetonide for intravitreal administration: preparation, characterization and in vivo evaluation, 5th Iranian Controlled Release Conference, October 4-6, 2011, Mashhad, Iran.

7)    Malaekeh-Nikouei B., Ramezani M., and Malaekeh-Nikouei M., Galactosylated liposmes-polyethyleneimine-DNA Nanocomplexes for gene delivery, Nano Thailand 2010, November 18-20, 2010, Thailand.

8)    Malaekeh-Nikouei B., Ramezani M., Motaharinia J., and Malaekeh-Nikouei M., The Cationic Liposome-Polyethyleneimine-DNA Complexes for Gene Delivery: Preparation, Characterization, and Transfection In Vitro, 12th Iranian Pharmaceutical Sciences Conference, August 2-5, 2010, Zanjan, Iran.

9)    Malaekeh-Nikouei B., Ramezani M., and Malaekeh-Nikouei M., Preparation, Characterization and Transfection Efficiency of Galactosylated Nanolipoplexes as a Gene Carrier, 2010 Singapore Symposium on Drug Delivery Systems, January 20-24, 2010, Singapore.

10)                       Malaekeh-Nikouei B., Abrishami  M.,Zarei-ghanavati S., Soroush D., Majid Rouhbakhsh M., Jaafari M. R.,  Preparation, characterization and in vivo evaluation of nanoliposomes encapsulated bevacizuamb (Avastin) for intravitreal administration, The Specialized Congress of Nanomedicine, Nanobiotechnology, Nanobiosensors and Nanomaterials, July 14-16, 2009 , Mashhad, Iran.

11)                       Malaekeh-Nikouei B., Ramezani M., Nazari S., Khakshour T., Preparation, characterization and transfection efficiency of nanoliposmes modified with lipopolymers constructed from polyethyleneimine and acrylate derivatives, 4th Iranian Controlled Release Conference, October 6-8, 2009, Zanjan, Iran

12)                       Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., Afshin Samiei, The effect of phospholipid type and size on immunosuppressive activities of liposomes encapsulated with cyclosporine A, 11th Liposome Research Days Conference, July 2008, Yokohama, Japan.

13)                       Malaekeh-Nikouei B., Ramezani M., Malaekeh-Nikouei M., Kazemi Oskuee R., Preparation, characterization and transfection efficiency of nanoliposomes modified with oligoamines as gene carrier, 11th Iranian Pharmaceutical Sciences Conference, Aug 2008, Kerman, Iran.

14)                       Gholamzadeh A., Ashari H., Malaekeh-Nikouei B., Sajadi Tabassi S.A., Evaluation of sulphobutylether β-cyclodextrin and hydroxypropyl γ-cyclodextrin complexation on aqueous solubility of fluorometholone, 11th Iranian Pharmaceutical Sciences Conference, Aug 2008, Kerman, Iran.

15)                       Shahsavand S., Mehri S., Moallem S.A., Mosavi S.H., Malaekeh-Nikouei B., Assessment of cytotoxic and apoptogenic properties of crocin and its nanoliposomes in various cancer cell lines, 11th Iranian Pharmaceutical Sciences Conference, Aug 2008, Kerman, Iran.

16)                       Mehri S., Shahsavand S., Moallem S.A., Mosavi S.H., Malaekeh-Nikouei B., Assessment of cytotoxic and apoptogenic properties of safranal and its nanoliposomes in various cancer cell lines, 11th Iranian Pharmaceutical Sciences Conference, Aug 2008, Kerman, Iran.

17)                       Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., Preparation, characterization and mucoadhesive evaluation of chitosan coated liposomes containing cyclosporine A, The Third Iranian Conference of Novel Drug Delivery Systems, June 2007, Tehran, Iran.

18)                       Sajadi S. A., Malaekeh-Nikouei B., Jaafari M. R., Davies N. M., The effect of complexation on characteristics of and drug release from PLGA microspheres loaded by cyclosporine-cyclodextrin complex, 33rd Annual Meeting and Exposition of the Controlled Release Society, July 2006, Vienna, Austria.

19)                       Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., Preparation and characterization of chitosan coated microspheres encapsulated with cyclosporine A, 10th Iranian Pharmaceutical Sciences Conference, Aug 2006, Tehran, Iran.

20)                       Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., SamieiA., The enhancement of immunosuppressive effects of cyclosporine A on human T-cells using fusogenic liposomes, 10th Iranian Pharmaceutical Sciences Conference, Aug 2006, Tehran, Iran.

21)                       Sajadi S. A., Malaekeh-Nikouei B., Jaafari M. R., Preparation and characterization of biodegradable microspheres encapsulated with Cyclosporine A using different grades of PLGA, 1ST Pharmaceutical Sciences Fair & Exhibition, June 2005, Nice, France.

22)                       Malaekeh-Nikouei B., et al., Formulation of topical liposomes encapsulated with triamcinolone and comparison of their anti-inflammatory effects with available conventional topical ointment in mice, 9th Seminar of Pharmaceutical Sciences, Aug 2004, Tabriz, Iran.

23)                       Malaekeh-Nikouei B., et al., Preparation and characterization of biodegradable microsphere encapsulated with Cyclosporine A using different grades of PLGA, 9th Seminar of Pharmaceutical Sciences, Aug 2004, Tabriz, Iran.

24)                       Malaekeh-Nikouei B., et al., Comparison of different physicochemical analysis methods of H2-blockers, 1st Seminar of Pharmaceutical Methodology, Sep 2001, Mashhad, Iran.

25)                       Hasanzadeh D., Malaekeh-Nikouei B., Development of quantitative FT-IR analysis of H2-blockers: comparison with the HPLC methodology, Proc. 3rd World Meeting APV/APGI, April 2000, Berlin, Germany.

 

Book:

1)    Stuart S., Modern Infrared Spectroscopy, 2002, Tabriz University of Medical Sciences (Translation to Persian).

2)    Malaekeh-Nikouei B., Hanafi-Bojd M.Y., Aghebati T., Mosallaei N., 2011, Nanoparticulate drug delivery systems, Mashhad University of Medical Sciences, (Writing in Persian).

 

امتیاز کاربران

ستاره غیر فعالستاره غیر فعالستاره غیر فعالستاره غیر فعالستاره غیر فعال

Curriculum Vitae

 

Ali Badiee (Pharm. D., Ph. D.)

 

Assistant Professor in Pharmaceutics,

School of Pharmacy,

Mashhad University of Medical Sciences,

Mashhad-Iran

P.O.Box: 91775-1365

Mobile phone: 09153588537

Phone: 0098-511-8823255(Office)

Fax: 0098-511-8823251

E-mail: Badieeaاین آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید or این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید

Date of birth: September 20th, 1975

Place of birth: Gorgan, Iran

Marital status: Married

 

Education and training:

- Research fellowship: School of Pharmacy, University of Queensland, Australia.

- Ph.D. (Pharmaceutics): School of Pharmacy, Mashhad University of Medical Science (2001-2006).

- Pharm. D: School of Pharmacy, Mashhad University of Medical Science (1993 -1999).

 

Workshops:

- ‘Basic pharmacokinetic-pharmacodynamics in drug development’, Tehran, 2003.

- ‘Internal evaluation of education planning’, Tehran, 2007.

- ‘Curriculum planning’, Mashhad, 2008.

- ‘Introduction to medical digital library resources’, Mashhad, 2008.

- ‘Biosafety practices and vaccine production’, Mashhad, 2009.

- ‘Good Clinical Practice’, Mashhad, 2009.

- ‘Microsoft Outlook’, Mashhad, 2009.

- ‘Microsoft Word’, Mashhad, 2009.

- ‘Microsoft Outlook’, Mashhad, 2009.

- ‘Microsoft Word’, Mashhad, 2009.

- ‘Microsoft Excel’, Mashhad, 2009.

- ‘Whole animal body imaging’, Tehran, 2010.

- ‘Overview of vaccine products and their quality controls’, Tabriz, 2010.

- ‘Scientific articles writing and publishing methods’, Mashhad, 2010.

- ‘Introduction to research and research methods’, Mashhad, 2010.

- ‘Introduction to atomic force microscopy (AFM) and particle size analysis (PSA)’, Zanjan, Iran.

 

 

Research interests:

Targeted drug and/or vaccine nanodelivery systems, Peptide and protein formulation, Liposome based vaccination, Liposomal drug/gene delivery.

 

Thesis:

- Research fellowship project: Targeting to dendritic cells with anti DEC-205 Immunoliposomes: an effective procedure for vaccination or immunotherapy against cancer

- Ph.D. thesis: Formulation, characterization, and evaluation of immune response of liposomes co-encapsulated leishmania antigens and CpG oligodeoxynucleotide adjuvant against leishmaniasis in murine model

- Pharm. D. thesis: Crystal habit modifications of Ibuprofen and their tableting and physico-mechanical characteristics

 

Supervisors:

- Research fellowship project: Prof. Derek Hart, Dr. Masato Kato, Dr. Nigel Davies

- Ph.D. thesis: Dr. Mahmoud Reza Jaafari, Dr. Ali Khamesipour

- Pharm. D. thesis: Dr. Hadi Afrasiabi Garekani

 

Honors & Awards:

1) The best PhD dissertation in 11th Iranian seminar of pharmaceutical scientists, Kerman, Iran, 2008 (Offered by Iranian association of pharmaceutical scientists).

2) Second rank in modern technology, The 13th Razi Research Festival on Medical Sciences, Iran, 2007

 

Publications:

- H. Hejazi, M. Tasbihi, M. R. Jaafari, A. Badiee, N. Pestechian, A. Javadi, A. Khamesipour, 2010. The role of liposomal CpG ODN on the course of L. major infection in BALB/c mice, Iranian J Parasitol, 5(1): 47-54.

 

- A. Badiee, M. R. Jaafari, A. Khamesipour, 2009. The role of liposome size on the type of immune response and protection rate induced against leishmaniasis in BALB/c mice: rgp63 as a model antigen, (submitted in Journal of Nanoparticle Research).

- A. Badiee, M. R. Jaafari, A. Khamesipour, A. Samiei, D. Soroush, M. T. Kheiri, F. Barkhordari, W. R. McMaster, F. Mahboudi, 2009. The role of liposome charge on immune response generated in BALB/c mice immunized with rgp63, Experimental Parasitology,121, 362-369.

 

- A. Badiee, M. R. Jaafari, A. Khamesipour, 2009. Enhancement of immune response and protection in BALB/c mice immunized with liposomal recombinant major surface glycoprotein of Leishmania (rgp63): The role of bilayer composition, Colloids and Surfaces B: Biointerfaces, 74(1):37-44.

 

- A. Badiee, M. R. Jaafari, A. Samiei, D. Soroush, A. Khamesipour, 2008. Co-encapsulation of CpG ODN with rLmSTI1 in liposome enhances immune response and protection against leishmaniasis in immunized BALB/c mice, Clinical and Vaccine Immunology, 15, 668-674.

 

- A. Badiee, N. M. Davies, K. McDonald, K. Radford, H. Michiue, D. N. J. Hart, M. Kato, 2007. Enhanced delivery of immunoliposomes to human dendritic cells by targeting the multilectin receptor DEC-205, Vaccine, 25, 4757–4766.

 

- M. R. Jaafari, A. Badiee, A. Samiei, D. Soroush; M. T. Kheiri, F. Barkhordari, A. Khamesipour, W. R. McMaster, F. Mahboudi, 2007. The role of CpG ODN in enhancement of immune response and protection in BALB/c mice immunized with recombinant major surface glycoprotein of Leishmania (rgp63) encapsulated in cationic liposome, Vaccine, 25, 6107–6117.

 

- A. Badiee, M. R. Jaafari, A. Khamesipour, 2007. Leishmania major: Immune   response in BALB/c mice immunized with stress-inducible protein 1 encapsulated in liposomes, Experimental Parasitology,115, 127-134.

 

- Y. Sohrabi, M. R. Jaafari, A. Badiee, S. H. Hejazi, S. E. Eskandari, A. M. Mohammadi, A. Khamesipour, 2007. Evaluation of immune response against autoclaved Leishmania major incorporated into positively charged liposomes in BALB/c mice, Iranian Journal of Dermatology, 10, 37-53.

 

- A. Badiee, M. R. Jaafari, A. Samiei, D. Soroush, A. Khamesipour, 2006. Immune response evaluation against leishmaniasis using liposomes containing rLmSTI1 in murine model, Iranian Journal of Basic Medical Sciences, 8, 215-225.

 

- H. A. Garekani, F. Sadeghi, A. Badiee, S. A. Mostafa, A. R. Rajabi-Siahboomi, 2001. Crystal habit modifications of ibuprofen and their physico-mechanical characteristics, Drug Development and Industrial Pharmacy, 27, 803-809.

 

- H. A. Garekani, F. Sadeghi, A. Badiee, 1999, Investigation of the physico-mechanical properties of modified crystals of ibuprofen, Iranian Journal of Basic Medical Sciences, 2, 8-17.

 

 

Conference presentations:

1) A. Badiee, Y. Sohrabi, M. Ghaemi, Protective effect of non-Ionic surfactants on acidic hydrolysis process of Aspirin. Proceeding of the 3rd congress of Iranian pharmacy students, (Iran, 1996).

2) S. Shojaiee, Y. Sohrabi, A. Badiee, Effect of Gentamycine on stimulation of immune system in rabbit. Proceeding of the 4th congress of Iranian pharmacy students, (Iran, 1997).

3) H. A. Garekani, F. Sadeghi, A. Badiee, A. R. Rajabi-Siahboomi, Crystal habit modifications of ibuprofen and their physico-mechanical characteristics., 19th Pharmaceutical Technology Conference, (Italy, 2000).

4) A. Badiee, M. R. Jaafari, A. Samiei, D. Soroush, J. Webb, A. Khamesipour, Immunization of BALB/c mice against cutaneous leishmaniasis using liposomes containing rLmSTI1 and CpG ODNs, Third World Congress on Leishmaniosis, (Italy, 2005).

5) M. R. Jaafari, A. Badiee, A. Samiei, D. Soroush, A. Khamesipour, M. Amani, F. Mahboudi, Vaccination of BALB/c mice against cutaneous leishmaniasis using liposomes containing rgp63 and CpG ODNs, Third World Congress on Leishmaniosis, (Italy, 2005, oral presentation).

6) A. Badiee, M. Kato, D. N. J. Hart, N. M. Davies, Uptake of anti DEC205 IgG immunoliposomes by immature and mature dendritic cells: Comparison with control IgG immunoliposomes and conventional liposomes, 33rd Annual Meeting & Exposition of the Controlled Release Society, (Austria, 2006).

7) A. Badiee, M. R. Jaafari, A. Khamesipour, Immunization of BALB/c mice against cutaneous Leishmaniasis by Leishmania major strees inducible protein 1 encapsulated in liposomes,10th Iranian Pharmaceutical Ssciences Conference, (Iran, 2006).

     8) A. Badiee, M. Kato, D. N. J. Hart, N. M. Davies, Enhanced delivery of anti-hDEC-205 immunoliposomes to human dendritic cells: A strategy for DC-based cancer immunotherapy, 19th Asia Pacific Cancer Conference, (Iran, 2007, oral presentation).

                 9) M. R. Jaafari, A. Badiee, A. Samiei, D. Soroush, A. Khamesipour, Enhancement of immune response and protection in BALB/c mice immunized with liposomal recombinant major surface glycoprotein of Leishmania (rgp63): The role of bilayer composition, 3rd ILS Annual Meeting: Liposome Advances, (UK, 2007).

      10) M. R. Jaafari, A. Badiee, A. Samiei, D. Soroush; M. T. Kheiri, F. Barkhordari, A. Khamesipour, F. Mahboudi, The role of liposome charge on immune response generated in BALB/c mice immunized with rgp63, 11th Liposome Research Days Conference, (Japan, 2008).

11) A. Badiee, M. Kato, D. N. J. Hart, N. M. Davies, Preparation and characterization of anti-hDEC-205 immunoliposome nanoparticles for targeting to human dendritic cells, The Specialized Congress And International Exhibition Of Nanomedicine, Nanobiotechnology, Nanobiosensors And Nanomaterials, (Iran, 2009, oral presentation).

12) M.R. Jaafari, A. Badiee,A. Khamesipour, A. Samiei, D Soroush, A Abbasi, M Tavassoti Kheiri, F Barkhordari, F Mahboudi, Immunization of BALB/c Mice against Leishmaniasis using LPD Nanoparticles Containing rgp63 and rLmaCIN Prepared with CpG Oligodeoxynucleotides, The Specialized Congress And International Exhibition Of Nanomedicine, Nanobiotechnology, Nanobiosensors And Nanomaterials, (Iran, 2009).

13) A. M. Eslahtalab, A. Badiee, Dendritic Cells-based Cancer Vaccines: The Role of Lipid-based Nanoparticles, The Specialized Congress And International Exhibition Of Nanomedicine, Nanobiotechnology, Nanobiosensors And Nanomaterials, (Iran, 2009).

14) H. Alavizade, A. Badiee, M. R. Jaafari, Lipid-Protamine-DNA (LPD) Nanoparticles as a Aaccine Delivery System for Cancer Immunotherapy, The Specialized Congress And International Exhibition Of Nanomedicine, Nanobiotechnology, Nanobiosensors And Nanomaterials, (Iran, 2009).

15) M. Amin, A. Badiee, M. R. Jaafari, Nanoparticulate Systems in Cancer Detection and Therapy, The Specialized Congress And International Exhibition Of Nanomedicine, Nanobiotechnology, Nanobiosensors And Nanomaterials, (Iran, 2009).

16) A. Badiee, M. R. Jaafari, A. Khamesipour, Formulation, characterization and evaluation of immune response of liposomes containing leishmania antigen and CpG ODN against leishmaniasis in murine model, 4th Iranian Controlled Release Conference (Iran, 2009, oral presentation).

17) A. H. Alavizadeh, M. R. Jaafari, A. Badiee, A. Khamesipour, A. Jalali, A. Abbasi, Evaluation of lesion development and type of immune response generated in mice inoculated with L. major mixed with LPD Nanoparticles containing CpG ODN, 3rd Conference on Nanotechnology (Iran, 2010, oral presentation)